9 Results for "

white matter

" in MedChemExpress (MCE) Product Catalog:
Products (9)

9 Results for "white matter" in MCE Product Catalog:

4
4 Cited Publications
Cat. No.: HY-W040821
CAS No.: 454-29-5
DL-Homocysteine is a weak neurotoxin, and can affect the production of kynurenic acid in the brain. DL-Homocysteine is correlated with Vitamin B12, renal functions and folate levels, affects the cross-sectional cognition indirectly through white matter microstructural integrity .
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Cat. No.: HY-P10936A
Target:  

Aquaporin

AQP4 (201-220) TFA is an encephalitogenic epitope of AQP-4. AQP4 (201-220) TFA can induce experimental autoimmune encephalomyelitis (EAE) (characterized by midline lesions in the brain, retinal pathology, and lesions at the grey matter/white matter border zone in the spinal cord). AQP-4 is a target antigen in neuromyelitis optica .
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Cat. No.: HY-153399A
CAS No.: 2945073-88-9
Synonyms: ABBV-CLS-7262 THAM sodium
Fosigotifator (ABBV-CLS-7262) THAM sodium is a brain penetrant, orally active EIF2b (eukaryotic initiation factor) activator. Fosigotifator THAM sodium stabilizes the elF2B complex and boosts the activity, including that of complexes carrying pathogenic vanishing white matter (VWM) mutations. Fosigotifator THAM sodium is an integrated stress response inhibitor (ISRI). Fosigotifator THAM sodium can be used for amyotrophic lateral sclerosis research .
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Cat. No.: HY-P10936
CAS No.: 2104700-59-4
Target:  

Aquaporin

AQP4 (201-220) is an encephalitogenic epitope of AQP-4. AQP4 (201-220) can induce experimental autoimmune encephalomyelitis (EAE) (characterized by midline lesions in the brain, retinal pathology, and lesions at the grey matter/white matter border zone in the spinal cord). AQP-4 is a target antigen in neuromyelitis optica .
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Cat. No.: HY-P10887
CAS No.: 2988012-71-9
Synonyms: AV-001
Pegevongitide (AV-001) is a Tie2 agonist. Pegevongitide resists the increased endothelial cell permeability induced by SARS-CoV-2 infection. Pegevongitide activates the angiogenin (angiogenin)/Tie2 signaling pathway. Pegevongitide reduces perivascular space dilation and upregulates perivascular Aquaporin-4 expression. Pegevongitide decreases the expression of TNF-α, PAI-1, CXCL9 and P-selectin, improves white matter integrity, enhances cognitive function and exerts neuroprotective effects. Pegevongitide improves white matter integrity in middle-aged rats with vascular dementia induced by multiple microinfarctions . Pegevongitide can be used in related research on diseases such as COVID-19 and vascular dementia .
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Cat. No.: HY-153399
CAS No.: 2415715-84-1
Synonyms: ABBV-CLS-7262
Fosigotifator (ABBV-CLS-7262) is a brain penetrant, orally active EIF2b (eukaryotic initiation factor) activator. Fosigotifator stabilizes the elF2B complex and boosts the activity, including that of complexes carrying pathogenic vanishing white matter (VWM) mutations. Fosigotifator is an integrated stress response inhibitor (ISRI). Fosigotifator can be used for amyotrophic lateral sclerosis research .
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Cat. No.: HY-113429
CAS No.: 70110-50-8
Synonyms: Cholesteryl cervonate
Research Areas:  

Metabolic Disease

Cholesteryl docosahexaenoate (Cholesteryl cervonate) is a biomarker used to diagnose white matter lesions in the brain .
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Cat. No.: HY-W040821R
CAS No.: 454-29-5
Metoprolol acid (Standard) is the analytical standard of Metoprolol acid. This product is intended for research and analytical applications. Metoprolol acid (Atenolol acid) is a urinary metabolite with no pharmacological activity. Metoprolol acid does not exert its pharmacological effects in vivo. Metoprolol acid can be detected by solid phase extraction and reversed phase high performance liquid chromatography. The analysis of metoprolol acid requires specific conditions, such as the use of fluorescence detection and specific eluents .
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Cat. No.: HY-113203A
CAS No.: 27561-79-1
Target:  

Endogenous Metabolite

Research Areas:  

Neurological Disease

Putreanine dihydrochloride is an alkaline diamino monocarboxylic acid amino acid that exists exclusively in the central nervous system of mammals and birds. Putreanine dihydrochloride reaches its highest concentration in the caudal region of the brain. Putreanine dihydrochloride appears in the brain tissue of rats 2 weeks after birth, and its concentration gradually increases to adult levels over several months .
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