Putreanine dihydrochloride

Name: Putreanine dihydrochloride
Brand: MedChemExpress
SKU: HY-113203A
Rating: 4.5 (1 reviews)

Cat. No.: HY-113203A Purity: 99.60%: Data Sheet
COA

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Putreanine dihydrochloride is an alkaline diamino monocarboxylic acid amino acid that exists exclusively in the central nervous system of mammals and birds. Putreanine dihydrochloride reaches its highest concentration in the caudal region of the brain. Putreanine dihydrochloride appears in the brain tissue of rats 2 weeks after birth, and its concentration gradually increases to adult levels over several months.

For research use only. We do not sell to patients.

Putreanine dihydrochloride Chemical Structure

CAS No. : 27561-79-1

Size	Stock	Quantity
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	Get quote
100 mg	Get quote

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Based on 1 publication(s) in Google Scholar

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Purity & Documentation
References
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Description

In Vitro

Putreanine dihydrochloride can be isolated from post-mortem bovine brain tissue via sequential ion-exchange chromatography and crystallization^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Putreanine dihydrochloride exists exclusively in the central nervous system of 6-month-old healthy rats and is undetectable in peripheral organs^[1].
Putreanine dihydrochloride first appears in the brain tissue of 2-week-old healthy rats, with its concentration increasing gradually and reaching adult levels at 3-6 months of age^[1].
Putreanine dihydrochloride exists in multiple regions of the central nervous system of healthy rabbits, with the highest average concentrations detected in the brainstem and cerebellum, while it is undetectable in the sciatic nerve^[1].
Putreanine dihydrochloride is concentrated in the caudal brain regions and white matter of the central nervous system in healthy cattle, with the highest concentration in the pons, and it is not detected in the retina^[1].
Putreanine dihydrochloride exists exclusively in the central nervous system of healthy mammals and birds, but cannot be detected in the brains of amphibians and fish, nor in the peripheral organs of mammals and birds^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

233.14

Formula

C₇H₁₈Cl₂N₂O₂

CAS No.

27561-79-1

Appearance

Solid

Color

White to off-white

SMILES

O=C(CCNCCCCN)O.Cl.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

DMSO : 100 mg/mL (428.93 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	4.2893 mL	21.4463 mL	42.8927 mL
5 mM	0.8579 mL	4.2893 mL	8.5785 mL
10 mM	0.4289 mL	2.1446 mL	4.2893 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

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Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.60%

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Data Sheet (268 KB) SDS (252 KB)

COA (242 KB) HNMR (289 KB) LCMS (322 KB)

Handling Instructions (2659 KB)

References

[1]. Kakimoto Y, et al. Putreanine, N-(4-Aminobutyl)-3-aminopropionic Acid: An amino acid occurring uniquely in the mammalian central nervous system. Journal of Biological Chemistry. 1969 Nov 10;244(21):6003-6.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	4.2893 mL	21.4463 mL	42.8927 mL	107.2317 mL
	5 mM	0.8579 mL	4.2893 mL	8.5785 mL	21.4463 mL
	10 mM	0.4289 mL	2.1446 mL	4.2893 mL	10.7232 mL
	15 mM	0.2860 mL	1.4298 mL	2.8595 mL	7.1488 mL
	20 mM	0.2145 mL	1.0723 mL	2.1446 mL	5.3616 mL
	25 mM	0.1716 mL	0.8579 mL	1.7157 mL	4.2893 mL
	30 mM	0.1430 mL	0.7149 mL	1.4298 mL	3.5744 mL
	40 mM	0.1072 mL	0.5362 mL	1.0723 mL	2.6808 mL
	50 mM	0.0858 mL	0.4289 mL	0.8579 mL	2.1446 mL
	60 mM	0.0715 mL	0.3574 mL	0.7149 mL	1.7872 mL
	80 mM	0.0536 mL	0.2681 mL	0.5362 mL	1.3404 mL
	100 mM	0.0429 mL	0.2145 mL	0.4289 mL	1.0723 mL