Fosigotifator THAM sodium

(Synonyms: ABBV-CLS-7262 THAM sodium)

Fosigotifator (ABBV-CLS-7262) THAM sodium is a brain penetrant, orally active EIF2b (eukaryotic initiation factor) activator. Fosigotifator THAM sodium stabilizes the elF2B complex and boosts the activity, including that of complexes carrying pathogenic vanishing white matter (VWM) mutations. Fosigotifator THAM sodium is an integrated stress response inhibitor (ISRI). Fosigotifator THAM sodium can be used for amyotrophic lateral sclerosis research.

For research use only. We do not sell to patients.

  • CAS No.: 2945073-88-9
  • Formula: C29H37Cl2F2N3NaO12P
  • Molecular Weight:782.48
  • Storage:

    -20°C, stored under nitrogen

    * In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)

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