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Cat. No.: HY-151633

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hCAIX-IN-14

hCAIX-IN-14 (compound 5a) is a potent inhibitor of human CA IX with a K_i value of 134.8 nM.

For research use only. We do not sell to patients.

CAS No.: 77113-78-1
Formula: C₁₁H₁₇ClN₆O₂S
Molecular Weight:332.81

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

hCAIX-IN-14 Chemical Structure

CAS No.: 77113-78-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

hCAIX-IN-14 (compound 5a) is a potent inhibitor of human CA IX with a K_i value of 134.8 nM^[1].

IC₅₀ & Target^[1]

hCA IX

134.8 nM (Ki)

All Carbonic Anhydrase Isoforms :

Chemical Information

CAS No. 77113-78-1
Molecular Weight 332.81
Formula C₁₁H₁₇ClN₆O₂S
SMILES

O=S(C1=CC=C(N2C(C)(C)N=C(N)N=C2N)C=C1)(N)=O.Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zain-Alabdeen AI, et al. Synthesis and anticancer activity of new benzensulfonamides incorporating s-triazines as cyclic linkers for inhibition of carbonic anhydrase IX. Sci Rep. 2022 Oct 6;12(1):16756. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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hCAIX-IN-14

All Carbonic Anhydrase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

hCAIX-IN-14 Related Classifications

HY-151633 Related Classifications