Sorbitan monopalmitate
Based on 1 Customer Validation
Sorbitan monopalmitate is a food-grade, non-ionic emulsifier that exhibits oral activity. Sorbitan monopalmitate functions as a crystallization modifier, promoting the aggregation of spherical mango butter crystals, introducing lattice defects, and regulating the crystallization rate of mango butter. Sorbitan monopalmitate serves as a component of precursor vesicle gels, enabling the controlled and sustained release of drugs and facilitating the preparation of stable transdermal delivery formulations.
For research use only. We do not sell to patients.
- CAS No.: 26266-57-9
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Storage:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Sorbitan monopalmitate (0-5% w/w; 30 min) modulates the color properties of mango butter formulations. Compared with the group supplemented with 1% w/w Sorbitan monopalmitate, supplementation with 5% w/w Sorbitan monopalmitate reduces yellowness and increases whiteness[2].
Sorbitan monopalmitate (1-5% w/w; 30 min) promotes the aggregation of spherical mango fat crystals and forms a denser fat crystal network, thereby modulating the crystal structure of mango fat[2].
Sorbitan monopalmitate (1-5% w/w; 5 h) improves the mechanical stability of mango butter formulations[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:(male) rat[1]
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Dosage:2,250 mg/kg bw per day
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Administration:p.o.; continuous daily feeding via diet; 2 years
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Result:Showed no alterations in growth pattern or survival compared to controls.
Found no abnormalities attributable to the experimental diet in blood studies or histopathological examination of the brain, spleen, pancreas, adrenal gland, bladder, bone marrow, heart, lymph nodes, lung, testicle, or muscle.
Chemical Information
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CAS No. 26266-57-9
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Appearance Solid
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Color White to off-white
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SMILES
O=C(CCCCCCCCCCCCCCC)OC[C@H]([C@@H]1[C@@H]([C@H](CO1)O)O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
Ethanol : 50 mg/mL (Need ultrasonic)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS), et al. Re-evaluation of sorbitan monostearate (E 491), sorbitan tristearate (E 492), sorbitan monolaurate (E 493), sorbitan monooleate (E 494) and sorbitan monopalmitate (E 495) when used as food additives. EFSA J. 2017;15(5):e04788. Published 2017 May 5. [Content Brief]
[2]. Das P, et al. Effect of sorbitan monopalmitate on the polymorphic transitions and physicochemical properties of mango butter. Food Chem. 2021;347:128987. [Content Brief]
[3]. Varshosaz J, et al. Sorbitan monopalmitate-based proniosomes for transdermal delivery of chlorpheniramine maleate. Drug Deliv. 2005;12(2):75-82. [Content Brief]
[4]. BELL JT Jr, et al. Polyoxyethylene sorbitan monopalmitate (tween 40) as a vehicle for oil red O fat stain. Stain Technol. 1959 Jul;34(4):219-21. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Sorbitan monopalmitate Related Classifications
HY-W129513 Related Classifications
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