26266-57-9
Chemical Structure
Sorbitan monopalmitate
- CAS No.: 26266-57-9
- Formula:N/A
- Molecular Weight:N/A
IUPAC Name: (R)-2-((2R,3R,4S)-3,4-dihydroxytetrahydrofuran-2-yl)-2-hydroxyethyl palmitate
InChIKey: IYFATESGLOUGBX-YVNJGZBMSA-N
SMILES: O=C(CCCCCCCCCCCCCCC)OC[C@H]([C@@H]1[C@@H]([C@H](CO1)O)O)O
Biological Activity: Sorbitan monopalmitate is a food-grade, non-ionic emulsifier that exhibits oral activity. Sorbitan monopalmitate functions as a crystallization modifier, promoting the aggregation of spherical mango butter crystals, introducing lattice defects, and regulating the crystallization rate of mango butter. Sorbitan monopalmitate serves as a component of precursor vesicle gels, enabling the controlled and sustained release of drugs and facilitating the preparation of stable transdermal delivery formulations[1][2][3][4].
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Sorbitan monopalmitate | Sorbitan monopalmitate is a food-grade, non-ionic emulsifier that exhibits oral activity. Sorbitan monopalmitate functions as a crystallization modifier, promoting the aggregation of spherical mango butter crystals, introducing lattice defects, and regulating the crystallization rate of mango butter. Sorbitan monopalmitate serves as a component of precursor vesicle gels, enabling the controlled and sustained release of drugs and facilitating the preparation of stable transdermal delivery formulations. | |||||||||||||||||||||
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References
- [1]. EFSA Panel on Food Additives and Nutrient Sources added to Food (ANS), et al. Re-evaluation of sorbitan monostearate (E 491), sorbitan tristearate (E 492), sorbitan monolaurate (E 493), sorbitan monooleate (E 494) and sorbitan monopalmitate (E 495) when used as food additives. EFSA J. 2017;15(5):e04788. Published 2017 May 5. [Content Brief]
- [2]. Das P, et al. Effect of sorbitan monopalmitate on the polymorphic transitions and physicochemical properties of mango butter. Food Chem. 2021;347:128987. [Content Brief]
- [3]. Varshosaz J, et al. Sorbitan monopalmitate-based proniosomes for transdermal delivery of chlorpheniramine maleate. Drug Deliv. 2005;12(2):75-82. [Content Brief]
- [4]. BELL JT Jr, et al. Polyoxyethylene sorbitan monopalmitate (tween 40) as a vehicle for oil red O fat stain. Stain Technol. 1959 Jul;34(4):219-21. [Content Brief]
