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Cat. No.: HY-B2106

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Polidocanol,Hydroxyl Value 40-60 mgKOH/g

(Synonyms: Polyoxyethylene lauryl ether; Polyoxyethyleneglycol Dodecyl Ether)

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Polidocanol is a sclerosing agent used successfully to treat extremity and esophageal varices and telangiectasias.

For research use only. We do not sell to patients.

Purity: 98.0%
CAS No.: 9002-92-0
Formula: (C₂H₄O)nC₁₂H₂₆O

Storage:

Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

Polidocanol,Hydroxyl Value 40-60 mgKOH/g Chemical Structure

CAS No.: 9002-92-0

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vivo
Chemical Information
Solvent & Solubility
- In Vitro
- In Vivo
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Polidocanol is a sclerosing agent used successfully to treat extremity and esophageal varices and telangiectasias.

In Vivo

Polidocanol (0.5%, 1%, and 2%) results in significantly more adhesions than tetracycline, whereas the effect of diluted polidocanol is similar to that of tetracycline in rats. The higher concentrations of polidocanol, of 0.5%, 1%, and 2% are more effective than either the diluted polidocanol or tetracycline against pleurodesis^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 9002-92-0
Appearance <41°C Solid,>45°C Liquid
Formula (C₂H₄O)nC₁₂H₂₆O
Color White to light yellow
SMILES

OCCCOCCCCCCCCCCCCC.[n]
Synonyms

Polyoxyethylene lauryl ether; Polyoxyethyleneglycol Dodecyl Ether
Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Pure form	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

H₂O : 50 mg/mL (Need ultrasonic)

DMSO : 50 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

View the Complete Stock Solution Preparation Table

In Vivo:

Working Solution

For the following dissolution methods, please prepare the working solution directly:

It is recommended to prepare fresh solutions and use them promptly within a short period of time.

The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: PBS

Solubility: 120 mg/mL; Clear solution; Need ultrasonic

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (261 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Cetin B, et al. Polidocanol at different concentrations for pleurodesis in rats. Surg Today. 2005;35(12):1066-9. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Polidocanol,Hydroxyl Value 40-60 mgKOH/g

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Biological Activity
- Description
- In Vivo
Chemical Information
Solvent & Solubility
- In Vitro
- In Vivo
Purity & Documentation
References

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Polidocanol,Hydroxyl Value 40-60 mgKOH/g

Biological Activity

Chemical Information

Solvent & Solubility

Purity & Documentation

References

Calculators

Help & FAQs

Polidocanol,Hydroxyl Value 40-60 mgKOH/g Related Classifications

HY-B2106 Related Classifications