1. MAPK/ERK Pathway
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  3. GNE-3511

GNE-3511 

Cat. No.: HY-12947 Purity: 99.98%
Handling Instructions

GNE-3511 is a dual leucine zipper kinase (DLK) inhibitor with a Ki of 0.5 nM.

For research use only. We do not sell to patients.

GNE-3511 Chemical Structure

GNE-3511 Chemical Structure

CAS No. : 1496581-76-0

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 140 In-stock
Estimated Time of Arrival: December 31
1 mg USD 84 In-stock
Estimated Time of Arrival: December 31
5 mg USD 144 In-stock
Estimated Time of Arrival: December 31
10 mg USD 192 In-stock
Estimated Time of Arrival: December 31
50 mg USD 648 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1128 In-stock
Estimated Time of Arrival: December 31
200 mg USD 1920 In-stock
Estimated Time of Arrival: December 31
500 mg   Get quote  
1 g   Get quote  

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Description

GNE-3511 is a dual leucine zipper kinase (DLK) inhibitor with a Ki of 0.5 nM.

Molecular Weight

440.49

Formula

C₂₃H₂₆F₂N₆O

CAS No.

1496581-76-0

SMILES

N#CC1=CC=NC(NC2=NC(N3CC(F)(F)CC3)=CC(C4CCN(C5COC5)CC4)=C2)=C1

Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 32 mg/mL (72.65 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2702 mL 11.3510 mL 22.7020 mL
5 mM 0.4540 mL 2.2702 mL 4.5404 mL
10 mM 0.2270 mL 1.1351 mL 2.2702 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Product Name:
GNE-3511
Cat. No.:
HY-12947
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