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Madrasin (Synonyms: DDD00107587; DD00107587; DDD-00107587)

Cat. No.: HY-100236 Purity: 99.49%
Data Sheet SDS Handling Instructions

Madrasin is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly.

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Madrasin Chemical Structure

Madrasin Chemical Structure

CAS No. : 374913-63-0

Size Price Stock Quantity
10 mM * 1 mL in DMSO $66 In-stock
5 mg $60 In-stock
10 mg $90 In-stock
25 mg $180 In-stock
50 mg $300 In-stock
100 mg $500 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Description

Madrasin is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly. Madrasin is cytotoxic at higher concentrations, although at lower concentrations it induces cell cycle arrest, promotes a specific reorganization of subnuclear protein localization, and modulates splicing of multiple pre-mRNAs in both HeLa and HEK293 cells.

References
Preparing Stock Solutions
Concentration Volume (DMSO) Mass 1 mg 5 mg 10 mg
1 mM 3.2119 mL 16.0596 mL 32.1192 mL
5 mM 0.6424 mL 3.2119 mL 6.4238 mL
10 mM 0.3212 mL 1.6060 mL 3.2119 mL
References
M.Wt

311.34

Formula

C₁₆H₁₇N₅O₂

CAS No.

374913-63-0

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

Solvent & Solubility

10 mM in DMSO

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Madrasin
Cat. No.:
HY-100236
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