1. Metabolic Enzyme/Protease
  2. Nampt

P7C3 

Cat. No.: HY-15976 Purity: 98.00%
Data Sheet SDS Handling Instructions

P7C3 is a NAMPT activator.

For research use only. We do not sell to patients.
P7C3 Chemical Structure

P7C3 Chemical Structure

CAS No. : 301353-96-8

Size Price Stock Quantity
10 mM * 1 mL in DMSO $55 In-stock
5 mg $50 In-stock
10 mg $80 In-stock
50 mg $320 In-stock
100 mg $580 In-stock
200 mg   Get quote  
500 mg   Get quote  

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Description

P7C3 is a NAMPT activator. P7C3 can enhance learning and memory in aged rats. Protects newborn neurons in the dentate gyrus by mitigating cell death. In vitro: Administration of active P7C3 chemicals to cells treated with doxorubicin, which induces NAD depletion, led to a rebound in intracellular levels of NAD and concomitant protection from doxorubicin-mediated toxicity. In vivo: P7C3 is orally bioavailable, crosses the blood-brain barrier, and is non-toxic at doses several fold higher than the efficacious dose.An easily administered pro-neurogenic compound. The administration of P7C3 is 10mg/ kg( IP) in rats. Administration of P7C3 to normal mice, as well as npas3-/- mice, enhance survival of neurons subsequent to their birth in the SGZ.

References
M.Wt

474.19

Formula

C₂₁H₁₈Br₂N₂O

CAS No.

301353-96-8

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
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Room temperature in continental US; may vary elsewhere

Solvent & Solubility

DMSO: ≥ 33 mg/mL

* "<1 mg/mL" means slightly soluble or insoluble. "≥" means soluble, but saturation unknown.

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Product Name:
P7C3
Cat. No.:
HY-15976
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