301353-96-8
301353-96-8
Chemical Structure
P7C3
- CAS No.: 301353-96-8
- Formula:C21H18Br2N2O
- Molecular Weight:474.19
IUPAC Name: 1-(3,6-dibromo-9H-carbazol-9-yl)-3-(phenylamino)propan-2-ol
InChIKey: FZHHRERIIVOATI-UHFFFAOYSA-N
SMILES: OC(CNC1=CC=CC=C1)CN2C3=CC=C(Br)C=C3C4=CC(Br)=CC=C24
Biological Activity: P7C3 is an orally bioavailable and blood-brain barrier penetrant aminopropyl carbazole, with neuroprotective effects. P7C3 can be used for the research of neurodegenerative diseases, including Parkinson's disease[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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P7C3 | 99.66% | P7C3 is an orally bioavailable and blood-brain barrier penetrant aminopropyl carbazole, with neuroprotective effects. P7C3 can be used for the research of neurodegenerative diseases, including Parkinson's disease. | ||||||||||||||||||||
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References
- [1]. Pieper AA et al. Discovery of a proneurogenic, neuroprotective chemical. Cell. 2010 Jul 9;142(1):39-51. [Content Brief]
- [2]. Pieper AA et al. P7C3 and an unbiased approach to drug discovery for neurodegenerative diseases. Chem Soc Rev. 2014 Oct 7;43(19):6716-26. [Content Brief]
- [3]. Chao Gu , et al. P7C3 Inhibits LPS-Induced Microglial Activation to Protect Dopaminergic Neurons Against Inflammatory Factor-Induced Cell Death in vitro and in vivo. Front Cell Neurosci. 2018; 12: 400. [Content Brief]
Keywords
