1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. GABA Receptor
  3. Picrotoxin

Picrotoxin (Synonyms: Cocculin)

Cat. No.: HY-101391 Purity: >98.0%
Handling Instructions

Picrotoxin is a noncompetitive antagonist of GABAA receptor.

For research use only. We do not sell to patients.

Picrotoxin Chemical Structure

Picrotoxin Chemical Structure

CAS No. : 124-87-8

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 66 In-stock
Estimated Time of Arrival: December 31
100 mg USD 60 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Publications Citing Use of MCE Picrotoxin

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Description

Picrotoxin is a noncompetitive antagonist of GABAA receptor.

Molecular Weight

301.29

Formula

C₁₅H₁₈O₇ . C₁₅H₁₆O₆

CAS No.

124-87-8

SMILES
Shipping

Room temperature in continental US; may vary elsewhere

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 30 mg/mL (99.57 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.3191 mL 16.5953 mL 33.1906 mL
5 mM 0.6638 mL 3.3191 mL 6.6381 mL
10 mM 0.3319 mL 1.6595 mL 3.3191 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (8.30 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (8.30 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.5 mg/mL (8.30 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: >98.0%

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  • Molarity Calculator

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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Picrotoxin
Cat. No.:
HY-101391
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