1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. GABA Receptor
  3. Anisatin

Anisatin 

Cat. No.: HY-N9506
Handling Instructions

Anisatin, a pure toxic substance isolated from the seeds of a Japanese plant (Illicium anisatum) acts as a picrotoxin-like, non-competitive GABA antagonist. Anisatin suppresses GABA-induced currents in a concentration-dependent manner with an EC50 of ~1.10 μM.

For research use only. We do not sell to patients.

Anisatin Chemical Structure

Anisatin Chemical Structure

CAS No. : 5230-87-5

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Description

Anisatin, a pure toxic substance isolated from the seeds of a Japanese plant (Illicium anisatum) acts as a picrotoxin-like, non-competitive GABA antagonist. Anisatin suppresses GABA-induced currents in a concentration-dependent manner with an EC50 of ~1.10 μM[1].

In Vitro

Anisatin inhibits [3H]diazepam binding enhanced by either GABA or pentobarbital, without affecting the basal specific binding to rat brain membranes[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

In mice, the LD50 reported for anisatin ranges from 0.76 to 1 mg/kg (po and ip)[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

328.31

Formula

C₁₅H₂₀O₈

CAS No.
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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Anisatin
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HY-N9506
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