Infection

Piloquinone is a phenanthrene compound. Piloquinone has inhibitory effect on mycobacterium and protozoa, but the effect is not strong.

Ulifloxacin (Standard) is the analytical standard of Ulifloxacin. This product is intended for research and analytical applications. Ulifloxacin is a broad-spectrum quinolone antibiotic. Ulifloxacin is the active metabolite of Prulifloxacin (HY-B0024). Ulifloxacin has anti-bacterial activity.

Crotoniazide (compound 9) is an isonicotinic acid hydrazide derivative with anti-HIV potential with an EC₅₀ value of 11 ug/mL.

Jietacin B is found to be resistant to nematode, it can kill Burs helenchus Lignicolus with the concentration of 0.25 μg/mL.

Enamidonin is a lipopeptide antibiotic. Enamidonin inhibits EGF-dependent [³H] thymidine involvement in Balb/MK cells (IC₅₀ is 10 μg/mL), and it can restore the deformed SRCTS-NRK form to the normal flat form (ED50 is 10 μg/mL). No antimicrobial activity.

Keto lovastatin is an impurity of Lovastatin (HY-N0504) with antibacterial activity. Lovastatin is a cell-permeable HMG-CoA reductase inhibitor used to lower cholesterol.

Bupirimate is a systemic fungicide that inhibits adenosine deaminase (ADA). Bupirimate is widely used in the cultivation of fruit trees, vegetables, flowers, and other crops to control powdery mildew.

Ramulosin has an antifungal effect and inhibits the germination of fungal meristems.

Ovalichromene B is a flavonone and phytochemical with an IC₅₀ of 78.83 ± 1.04 μM, found in the dry stem of Pongamia pinnata (L.) Pierre.Ovalichromene B inhibits lipopolysaccharide-induced nitric oxide production.Ovalichromene B exhibits high intestinal absorption, non-mutagenicity, non-hepatotoxicity, and no predicted hERG I or II channel inhibition.Ovalichromene B can be used for the research of neurodegenerative diseases.Ovalichromene B can be used for the research of carbapenem-resistant enterobacterales infections.

Memnobotrin A is an antibiotic found in Memnoniella echinata (JS6308). Memnobotrin A has inhibitory effect on NCI-460, MCF7 and SF-268 cell lines.

Dolutegravir-d₅ is deuterium labeled Dolutegravir. Dolutegravir (S/GSK1349572) is a highly potent and orally bioavailable HIV integrase strand transfer inhibitor with an IC₅₀ of 2.7 nM for HIV-1 integrase-catalyzed strand transfer. Dolutegravir (S/GSK1349572) inhibits HIV-1 viral replication with an IC₅₀ of 0.51 nM in peripheral blood mononuclear cells. Dolutegravir retains a high potency against the HIV-1 Y143R, N155H, and G140S/Q148H mutants (EC₅₀=3.6-5.8 nM).

4-O-Demethyl-11-deoxydoxorubicin is an anthracycline antibiotic with antibacterial and antitumor activities. 4-O-Demethyl-11-deoxydoxorubicin is cytotoxic to Hela cells.

Neoenactin B2 has strong anti-yeastlike and filamentous fungal effects.

Tioxolone (Standard) is the analytical standard of Tioxolone. This product is intended for research and analytical applications. Tioxolone is an inhibitor for the carbonic anhydrase. Tioxolone exhibits anti-leishmanial, antitumor, and anti-inflammatory activities. Tioxolone can be used in research of acne and psoriasis.

Decamethoxine (Standard) is the analytical standard of Decamethoxine (HY-108004). This product is intended for research and analytical applications. Decamethoxine (Septefril) is a cationic gemini surfactant. Decamethoxine exhibits strong bactericidal and fungicidal effects. Decamethoxine modifies the permeability of the microbial cell membrane, resulting in the destruction and death of diverse microorganisms.

LpxH-IN-2 (compound 014) is a potent LpxH inhibitor. LpxH-IN-2 shows antibacterial activity for E. coli.

Tioxacin is an orally active bactericide agent. Tioxacin combined with aliphatic amines has activities against G(+) and G (-) bacteria, including Escherichia coli resistant to Nalidixic acid (HY-B0398) and Pseudomonas aeruginosa.

Suricapavir is a potent viral replication inhibitor. Suricapavir shows antiviral activity.

SARS-CoV-2 Mpro-IN-55 is a SARS-CoV-2 M^pro inhibitor with a IC₅₀ value of 7.20 nM. SARS-CoV-2 Mpro-IN-55 shows limited inhibitory activity against SARS-CoV-2. SARS-CoV-2 Mpro-IN-55 can be used in research related to COVID-19.

5-Phenyllevulinic acid (4-Oxo-5-phenylpentanoic acid) is an endogenous fungal metabolite with inhibitory activity against the bacterium B. megaterium, the plant pathogenic fungus S. tritici, and the alga C. fusca. 5-Phenyllevulinic acid is also an intermediate in the synthesis of σ receptor ligands. 5-Phenyllevulinic acid holds potential for research in the field of anti-infection studies .