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United States

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Cat. No.: HY-161987

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LpxH-IN-2

LpxH-IN-2 (compound 014) is a potent LpxH inhibitor. LpxH-IN-2 shows antibacterial activity for E. coli.

For research use only. We do not sell to patients.

CAS No.: 2923230-41-3
Formula: C₂₇H₃₃ClF₂N₆O₄S
Molecular Weight:611.10

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

LpxH-IN-2 Chemical Structure

CAS No.: 2923230-41-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

LpxH-IN-2 (compound 014) is a potent LpxH inhibitor. LpxH-IN-2 shows antibacterial activity for E. coli^[1].

Chemical Information

CAS No. 2923230-41-3
Molecular Weight 611.10
Formula C₂₇H₃₃ClF₂N₆O₄S
SMILES

O=S(N1CCN(CC1)C2=CC(C(F)(F)[C@H]3CC[C@H](C(N)=O)CC3)=CC(Cl)=N2)(C4=CC=C(N5C[C@@H](N)CC5=O)C=C4)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Benediktsdottir A, et al. Design, synthesis, and in vitro biological evaluation of meta-sulfonamidobenzamide-based antibacterial LpxH inhibitors. Eur J Med Chem. 2024 Aug 22;278:116790. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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