Others

IR 650 Alkyne is a near-infrared fluorescent probe. The click chemistry reaction handle of IR 650 Alkyne is a terminal alkyne, which can undergo a 'copper-catalyzed alkyne-azide cycloaddition' reaction. Ex = 651nm, Em = 668nm.

ACu1 is a copper (I)-selective two-photon fluorescent probe that enables the visual imaging of Cu⁺ distribution in living cells and tissues.

Mito-Cu (II) is a mitochondria-targeted fluorescent probe (Ex/Em = 370/450 nM). Mito-Cu (II) specifically accumulates in mitochondria of living cells and enables real-time detection of exogenous Cu²⁺ within mitochondria of living cells. Mito-Cu (II) achieves "on-off-on" fluorescence switching through sequential exposure to Cu²⁺ and ethylenediaminetetraacetic acid (EDTA) (HY-Y0682). Its fluorescence is quenched after forming a 1:1 complex with Cu²⁺, and the fluorescence recovers when Cu²⁺ is chelated by EDTA.

IR 750 Maleimide is a near-infrared fluorescent dye composed of IRDye 750 near-infrared fluorophore and maleimide reactive group. IR 750 Maleimide can be applied to fluorescent labeling, imaging and detection.

IR 750 NHS ester is a near-infrared fluorescent dye composed of IRDye 750 near-infrared fluorophore and NHS ester reactive group. IR 750 NHS ester can be applied to fluorescent labeling, imaging and detection.

IR 680LT NHS ester is a fluorescent dye with an NHS ester moiety, which can be used to label antibodies, proteins, etc (Ex/Em = 675/694 nm).

PE-Cy5 is a tandem fluorescent dye commonly used in flow cytometry, immunofluorescence, and cell biology research. It is formed by the covalent linkage of two fluorescent molecules, namely phycoerythrin and CY5. PE-Cy5 binds to human FcγRI (CD64), and this binding can be blocked by human pooled serum, anti-CD64 monoclonal antibodies targeting the ligand-binding region, or aggregated IgG. PE-Cy5 supports three-color flow cytometry analysis, and whole blood staining can partially reduce its non-specific binding (Ex/Em = 450-500 nm/665 nm).

PE-Cy5.5 is a far-red emitting tandem dye designed based on the principle of fluorescence resonance energy transfer (FRET), and is widely used in multicolor flow cytometry. PE-Cy5.5 consists of phycoerythrin (PE) as the energy donor and the cyanine dye Cy5.5 as the energy acceptor. Upon excitation by blue or green laser light, PE absorbs energy and transfers it to Cy5.5 via FRET, ultimately resulting in Cy5.5 emitting characteristic far-red fluorescence (Ex/Em = 450-500 nm/698 nm).

PE-Cy7 is a tandem fluorescent dye composed of R-phycoerythrin (PE) coupled with the near-infrared dye Cy7. It is primarily excited by a 488 nm laser, with a maximum emission wavelength of approximately 780 nm. PE-Cy7 is widely used in flow cytometry and immunofluorescence staining.

PE-VF594 is a high-brightness fluorescent dye used in flow cytometry, primarily for labeling antibodies or streptavidin to help identify specific cell subpopulations. PE-VF594 is a tandem dye composed of two covalently linked fluorescent groups: one is phycoerythrin (PE), responsible for absorbing laser energy; the other is the receptor molecule VF594. Energy is transferred from PE to VF594 via fluorescence resonance energy transfer (FRET) mechanism (Ex/Em = 450-500 nm/614 nm) .

SMCC-PE is a dipalmitoylphosphatidylethanolamine derivative modified with the heterobifunctional crosslinker SMCC. SMCC-PE is an intermediate formed by conjugating the SMCC linker with R-phycoerythrin for antibody conjugation.

Ctrl-CSR1 is a non-responsive CSR1 control dye and a matched control dye with a photostable, hydrophilic silicon rhodol backbone. Ctrl-CSR1 lacks a copper-responsive receptor.

Ctrl-CCF1 is a control probe for CCF1. Ctrl-CCF1 can be used to distinguish copper-dependent responses from potential dye-dependent variations, such as cellular uptake, retention, subcellular accumulation, and changes in pH, redox or hydrophobic/hydrophilic environments.

CSF1 is a silicon-rhodamine-based, fluorescence-activatable probe with selectivity for Cu⁺. CSF1 colocalizes with the endoplasmic reticulum in live cells.

IR 680LT Maleimide is a near-infrared low-band fluorescence dye, composed of the IR 680LT dye core and maleimide groups. IR 680LT Maleimide is used for specifically labeling biologically active molecules containing sulfhydryl groups (Ex/Em = 679 nm/694 nm).

PtdIns-(4,5)-P2-biotin (DOPI-4,5-P2-biotin) sodium is a biotin-labeled phosphatidylinositol 4,5-bisphosphate (PIP2) derivative. PtdIns-(4,5)-P2-biotin sodium uses a biotin tag to capture and purify natural PIP2 molecules and their interacting proteins.

DiD is a long-chain carbocyanine dye. Carbocyanine dyes are widely used as Di to label cells, organelles, liposomes, viruses and lipoproteins (Ex/Em = 633/665 nm) .

Tubulin-RedTracker is a paclitaxel-derived fluorescent microtubule-binding probe. Tubulin-RedTracker induces F-actin cytoskeleton defects at relatively high concentrations. (Ex/Em=652/669).

Dnp-GPLG is a peptide that can be used as a negative control for matrix metalloproteinase (MMP) activity. MMPs can cleave peptides containing the Dnp-GPLG sequence.

Fluorescein-12-dGTP is a fluorescein-labeled deoxyguanosine triphosphate. Fluorescein-12-dGTP incorporates into complementary allele-specific primers at SNP sites, enabling FRET with cationic conjugated polymer PFP via DNA-PFP electrostatic interactions. Fluorescein-12-dGTP incorporates into G-allele-specific primers for homozygous G/G SNP genotypes to enable genotype discrimination. Fluorescein-12-dGTP serves as a fluorescently labeled nucleotide for homogeneous solution-based SNP and FRET genotyping assays (Ex/Em = 498/517 nm).