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Art. -Nr.: HY-D3284

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CSF1

CSF1 is a silicon-rhodamine-based, fluorescence-activatable probe with selectivity for Cu⁺. CSF1 colocalizes with the endoplasmic reticulum in live cells.

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CAS. Nr.: 2158211-22-2
Formel: C₃₉H₅₁F₃N₂O₂S₄Si
Molecular Weight:793.18

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

CSF1 Chemical Structure

CAS. Nr.: 2158211-22-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
- Clinical Trial
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

CSF1 is a silicon-rhodamine-based, fluorescence-activatable probe with selectivity for Cu⁺. CSF1 colocalizes with the endoplasmic reticulum in live cells^[1].

In Vitro

CSF1 serves as a fluorescent sensor for the specific recognition of Cu⁺ in aqueous buffer systems, with a K_d value of 0.49 pM, and its fluorescence response increases 17-fold upon binding to Cu⁺^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Clinical Trial

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS. Nr. 2158211-22-2
Molecular Weight 793.18
Formel C₃₉H₅₁F₃N₂O₂S₄Si
SMILES

CCSCCSCCN(CC1=CC=C(C(C(F)(F)F)=C1)C2=C3C=CC(C=C3[Si](C)(C4=C2C=CC(N5CCOCC5)=C4)C)=O)CCSCCSCC
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Jia S, et al. Tuning the Color Palette of Fluorescent Copper Sensors through Systematic Heteroatom Substitution at Rhodol Cores. ACS Chem Biol. 2018;13(7):1844-1852. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

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