1. Metabolic Enzyme/Protease
  2. Phosphatase

SHP394 

Cat. No.: HY-114397
Handling Instructions

SHP394 is an orally efficacious protein tyrosine phosphatase SHP2 inhibitor with an IC50 of 23 nM.

For research use only. We do not sell to patients.

SHP394 Chemical Structure

SHP394 Chemical Structure

CAS No. : 2055757-40-7

Size Stock
1 mg   Get quote  
5 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

SHP394 is an orally efficacious protein tyrosine phosphatase SHP2 inhibitor with an IC50 of 23 nM[1].

IC50 & Target

IC50: 23 nM (SHP2)[1]

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1254 mL 10.6268 mL 21.2535 mL
5 mM 0.4251 mL 2.1254 mL 4.2507 mL
10 mM 0.2125 mL 1.0627 mL 2.1254 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

470.51

Formula

C₂₀H₂₅F₃N₆O₂S

CAS No.

2055757-40-7

SMILES

NC1=C(C(N(C)C(N2CCC3(CO[[email protected]@H](C)[[email protected]]3N)CC2)=N1)=O)SC4=C(C(F)(F)F)N=CC=C4

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Inquiry Online

Your information is safe with us. * Required Fields.

Product name

 

Salutation

Applicant name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
SHP394
Cat. No.:
HY-114397
Quantity:

SHP394

Cat. No.: HY-114397