2055757-40-7
2055757-40-7
Chemical Structure
SHP394
- CAS. Nr.: 2055757-40-7
- Formula:C20H25F3N6O2S
- Molecular Weight:470.51
IUPAC Name: 6-amino-2-((3S,4S)-4-amino-3-methyl-2-oxa-8-azaspiro[4.5]decan-8-yl)-3-methyl-5-((2-(trifluoromethyl)pyridin-3-yl)thio)pyrimidin-4(3H)-one
InChIKey: QZHZIDHAIVAHMD-SMDDNHRTSA-N
SMILES: NC1=C(C(N(C)C(N2CCC3(CO[C@@H](C)[C@H]3N)CC2)=N1)=O)SC4=C(C(F)(F)F)N=CC=C4
Biological Activity: SHP394 is an orally active, selective and allosteric inhibitor of SHP2, with an IC50 of 23 nM[1].
| Art. -Nr. | Produktname | Reinheit | Beschreibung | Pricing | |||||||||||||||||||
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SHP394 | 99.66% | SHP394 is an orally active, selective and allosteric inhibitor of SHP2, with an IC50 of 23 nM. | ||||||||||||||||||||
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References
Keywords
