1. Membrane Transporter/Ion Channel
    Neuronal Signaling
  2. iGluR

Talampanel (Synonyms: GYKI-53773; LY-300164)

Cat. No.: HY-15079 Purity: 98.59%
Handling Instructions

Talampanel is a potent and selective AMPA-receptor antagonist, is a potential new antiepileptic drug (AED).

For research use only. We do not sell to patients.

Talampanel Chemical Structure

Talampanel Chemical Structure

CAS No. : 161832-65-1

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 106 In-stock
Estimated Time of Arrival: December 31
5 mg USD 96 In-stock
Estimated Time of Arrival: December 31
10 mg USD 144 In-stock
Estimated Time of Arrival: December 31
50 mg USD 492 In-stock
Estimated Time of Arrival: December 31
100 mg USD 792 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

Talampanel is a potent and selective AMPA-receptor antagonist, is a potential new antiepileptic drug (AED). Target: AMPA [1] in vitro: Talampanel is a glutamate receptor inhibitor with anti-seizure activity. in vivo: Talampanel reduces motoneuronal calcium in a mouse model of ALS, but its effi cacy declines as the disease progresses, suggesting that medication initiation in the earlier stages of the disease might be more effective. [2]

Clinical Trial
Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9641 mL 14.8205 mL 29.6410 mL
5 mM 0.5928 mL 2.9641 mL 5.9282 mL
10 mM 0.2964 mL 1.4821 mL 2.9641 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

337.37

Formula

C₁₉H₁₉N₃O₃

CAS No.

161832-65-1

SMILES

C[[email protected]@H]1CC2=C(C=C(OCO3)C3=C2)C(C4=CC=C(N)C=C4)=NN1C(C)=O

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Shipping

Room temperature in continental US; may vary elsewhere

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× = ×
C1   V1   C2   V2

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Product Name:
Talampanel
Cat. No.:
HY-15079
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Talampanel

Cat. No.: HY-15079