Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
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Drug Intermediate Related Products (4511)
Related Products (4511)
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Anhydroleucovorin (Standard)
0 ImagesCat. No.: HY-153039RCAS No.: 7444-29-3Rosiridin (Standard) is the analytical standard of Rosiridin. This product is intended for research and analytical applications. Rosiridin inhibits MAO A and MAO B with potential beneficial effect in depression and senile dementia. Rosiridin shows an inhibition of 83.8% against MAO B at 10 μM (pIC50=5.38).
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Cyclopropylmethyl bromide-d4
0 ImagesCat. No.: HY-Y1100SCAS No.: 1219805-93-2Cyclopropylmethyl bromide-d4 is the deuterium labeled Cyclopropylmethyl bromide (HY-Y1100). Cyclopropylmethyl bromide is an intermediate. Cyclopropylmethyl bromide can be used in the preparation of Firocoxib (HY-14670). Firocoxib (ML 1785713) is a potent, selective, orally active COX-2 inhibitor.
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Azidoethyl-oxime-Glucose-GalNAc
0 ImagesCat. No.: HY-402088CAS No.: 2823367-96-8Azidoethyl-oxime-Glucose-GalNAc is an intermediate for the synthesis of disaccharide Linker, which can be used for the synthesis of glycan site-directed ADC compounds.
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Polygonolide
0 ImagesCat. No.: HY-N19101CAS No.: 100560-66-5Polygonolide is an orally active isocoumarin anti-inflammatory agent. Polygonolide is present in the roots of Polygonum hydropiper and Persicaria hydropiper. Polygonolide inhibits the reversed passive Arthus reaction in rats. Polygonolide can be used in studies related to immune complex-induced inflammation.
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Woorenoside VIII
0 ImagesCat. No.: HY-N20628CAS No.: 195873-25-7Woorenoside VIII is a sesquiterpenoid compound with potential anti-inflammatory activity, which exists in Coptis japonica var. dissecta and its rhizomes.
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K-13
0 ImagesCat. No.: HY-120286CAS No.: 108890-90-0K-13 is a cyclic peptide compound synthesized by a specific organozinc reagent. Its synthesis process involves intermolecular and intramolecular Negishi cross-coupling reactions and is one of the shortest routes reported for the synthesis of such cyclic peptides.
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Camphorsulfonate sodium
0 ImagesCat. No.: HY-W272811CAS No.: 34850-66-3Camphorsulfonate sodium is an organic synthesis intermediate. Camphorsulfonate sodium can be used for synthesis of derivatives with SDH inhibitory activity through scaffold hopping. Camphorsulfonate sodium is also an organocatalyst that can be used as a pore-forming additive for modulating the porosity of the graphene film. Camphorsulfonate sodium can be used for binder-free porous graphene film and fungicide research.
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cis-2-Butene-1,4-diol
0 ImagesCat. No.: HY-W027631CAS No.: 6117-80-2cis-2-Butene-1,4-diol serves as a probe for investigating isomerization and hydrogenation/hydrogenolysis reactions. cis-2-Butene-1,4-diol is also a compound used in the synthesis of the antiviral agent Oxetanocin A. cis-2-Butene-1,4-diol undergoes hydrogenation and hydrogenolysis reactions over supported platinum catalysts, with negligible levels of isomerization.
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GL67
0 ImagesCat. No.: HY-149037CAS No.: 179075-30-0Synonyms: N4-Spermine cholesteryl carbamateGL67 (N4-Spermine cholesteryl carbamate) is a cationic lipid that serves as a non-viral siRNA delivery vector and a non-viral gene transfer vector. GL67 enhances the encapsulation efficiency of siRNA in liposomal formulations and promotes the cellular uptake of siRNA across cancer cell membranes. GL67 mediates the transduction of plasmid DNA into cells. GL67 can be used in drug delivery-related research.
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HGH fragment 176-191
0 ImagesCat. No.: HY-P11153HGH fragment 176-191 is a fragment of Human Growth Hormone. HGH fragment 176-191 binds with high affinity to Ki-67, MiB proteins, and estrogen receptors. HGH fragment 176-191 enhances the toxicity of chitosan nanoparticles loaded with Doxorubicin (HY-15142A) against breast cancer. HGH fragment 176-191 promotes lipolysis and fat utilization in mice. HGH fragment 176-191 can be used in research related to targeted drug delivery for cancer and lipid metabolism.
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Glycitein-7-O-methyl ether
0 ImagesCat. No.: HY-W783413CAS No.: 75199-40-5Synonyms: 6-MethoxyisoformononetinGlycitein-7-O-methyl ether (6-Methoxyisoformononetin) is an isoflavone antioxidant with a IC50 of 730.53 µg/mL. Glycitein-7-O-methyl ether exhibits weak free radical scavenging activity and shows no antibacterial activity against tested bacteria and fungi. Glycitein-7-O-methyl ether can be used in antioxidant-related research.
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L-Lactic acid calcium hydrate
0 ImagesCat. No.: HY-W105639CAS No.: 865717-20-0L-Lactic acid calcium hydrate is the calcium salt of L-Lactic acid. L-Lactic acid calcium hydrate is a building block that can be used as a precursor for the production of bioplastic polymer polylactic acid.
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2'-Hydroxyacetophenone-d7
0 ImagesCat. No.: HY-W739751CAS No.: 1189865-36-8Synonyms: o-Hydroxyacetophenone-d7; o-Acetylphenol-d72'-Hydroxyacetophenone-d7 (o-Hydroxyacetophenone-d7; o-Acetylphenol-d7) is the deuterium labeled 2'-Hydroxyacetophenone (HY-Y1426). 2'-Hydroxyacetophenone is found in alcoholic beverages. 2'-Hydroxyacetophenone is present in tomato, cassia, fried beef, rum, whiskey, cocoa, coffee and black tea. 2'-Hydroxyacetophenone is a flavouring ingredient. Building block in chemical synthesis.
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Isonicotinic acid (Standard)
0 ImagesIsonicotinic acid (Standard) is the analytical standard of Isonicotinic acid (HY-I0736). This product is intended for research and analytical applications. Isonicotinic acid is a pyridine carboxylic acid compound and also a metabolite of Isoniazid (HY-B0329). Derivatives of Isonicotinic acid exhibit antiviral activity against influenza viruses.
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Methoxycarbonyl isocyanate
0 ImagesCat. No.: HY-W178414CAS No.: 5843-42-5Methoxycarbonyl isocyanate can be used for compound synthesis.
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Hydrosorbaldehyde
0 ImagesCat. No.: HY-W747972CAS No.: 4440-65-7Hydrosorbaldehyde is a green leaf volatile and also the main contributor to the fresh, grassy aroma of tea leaves. Hydrosorbaldehyde undergoes irreversible conversion to (E)-2-hexenal via (Z)-3:(E)-2-hexenal isomerase (CsHI). Hydrosorbaldehyde plays a key role in protecting plants against biotic stresses (such as pathogens and insects) and acting as a signaling chemical.
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Guaietolin
0 ImagesCat. No.: HY-W412326CAS No.: 63834-83-3Synonyms: Guaietolin (INN); Guethral; GuethuralGuaietolin is an organic synthesis intermediate. Guaietolin is a marker of hypertension with significant reduced level in plasma metabolites. Guaietolin can be used for synthesis of sulfonamide esters with carbonic anhydrase inhibitory activity. Guaietolin can be used for glaucoma and hypertension research.
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1-Methylimidazole-d3-1
0 ImagesCat. No.: HY-59137S2CAS No.: 4166-68-11-Methylimidazole-d3-1 is the deuterium labeled 1-Methylimidazole. 1-Methylimidazole acts as a membrane performance regulator that promotes the formation of reverse osmosis membranes with a dense ultra-thin polyamide layer. Such membranes exhibit higher flux and salt rejection rate, while also conferring excellent pH stability to the membrane. 1-Methylimidazole can serve as a ligand for ruthenium (II) complexes to construct metal-based anticancer agents.
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ProX1-(SS)-DOTAGA
0 ImagesCat. No.: HY-185120ACAS No.: 3084147-67-8ProX1-(SS)-DOTAGA (Compound 12b) is the unbound portion of the radionuclide in the compound and can be used for targeted delivery to diseases characterized by ACP3 expression.
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H-Arg-Ser-Arg-OH
0 ImagesCat. No.: HY-134578CAS No.: 115035-42-2H-Arg-Ser-Arg-OH is a short peptide. H-Arg-Ser-Arg-OH is a motif of di-leucine and RSRR, it can be used to design larger peptides and compound.
