Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11038)
Related Products (11038)
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CLELFTELAED-(Lys-13C6,15N2) TFA
0 ImagesCat. No.: HY-P11521SCLELFTELAED-(Lys-13C6,15N2) TFA is the 13C- and 15N-labeled CLELFTELAED.
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2,5-Diethyl-3-methylpyrazine-d3
0 ImagesCat. No.: HY-W423245SCAS No.: 1335401-22-32,5-Diethyl-3-methylpyrazine-d3 is deuterated labeled 2,5-Diethyl-3-methylpyrazine.
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Dropropizine-d4
0 ImagesCat. No.: HY-W767656CAS No.: 2514953-45-6Synonyms: (±)-Dropropizine-d4; UCB-196-d4Dropropizine-d4 ((±)-Dropropizine-d4) is deuterium labeled Dropropizine. Dropropizine ((±)-Dropropizine) belongs to the phenylpiperazine group of organic compounds. Dropropizine is a peripheral antitussive agent that acts by inhibiting cough reflex through its action on the peripheral receptors and their afferent conductors .
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Sulthiame-d4
0 ImagesCat. No.: HY-108316SCAS No.: 1795021-05-4Sulthiame-d4 is the deuterium labeled Sultiame. Sultiame is a carbonic anhydrase inhibitor, widely used as an antiepileptic agent.
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Lansoprazole sulfone-13C6
0 ImagesCat. No.: HY-W008614S1CAS No.: 1261398-50-8Synonyms: AG-1813-13C6Lansoprazole sulfone (AG-1813)-13C6 is 13C labeled Lansoprazole sulfone (HY-W008614). Lansoprazole sulfone, Lansoprazole (HY-13662) metabolite, is a H+, K+-ATPase inhibitor. Lansoprazole sulfone has potential applications in duodenal ulcer, gastric ulcer, gastroesophageal reflux disease and Zolinger Ellison disease.
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Tri-p-tolyl phosphate-d21
0 ImagesCat. No.: HY-W654319CAS No.: 2469244-63-9Synonyms: Tricresyl phosphate-d21Tri-p-tolyl phosphate-d21 is the deuterium labeled Tri-p-tolyl phosphate.
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Efaproxiral-d6
0 ImagesCat. No.: HY-13619SCAS No.: 1246815-16-6Synonyms: RSR13-d6Efaproxiral (RSR13)-d6 is the deuterium labeled Efaproxiral (HY-13619). Efaproxiral is a haemoglobin (Hb) synthetic allosteric modifier. Efaproxiral decreases Hb-oxygen (O2) binding affinity and enhances oxygenation of hypoxic tumours during radiation therapy .
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Zafirlukast-d6
0 ImagesCat. No.: HY-17492S3CAS No.: 1109278-84-3Synonyms: ICI 204219-d6Zafirlukast-d6 is deuterated labeled Zafirlukast (HY-17492). Zafirlukast (ICI 204219) is a potent orally active leukotriene D4 (LTD4) receptor antagonist. Zafirlukast shows anti-asthmatic, anti-inflammatory and anti-bacterial effects.
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Ritonavir-13C3
0 ImagesCat. No.: HY-W653853CAS No.: 1217673-23-8Synonyms: ABT 538-13C3; RTV-13C3Ritonavir-13C3 is 13C labeled Ritonavir. Ritonavir (ABT 538) is an inhibitor of HIV protease used to treat HIV infection and AIDS. Ritonavir is also a SARS-CoV 3CLpro inhibitor with an IC50 of 1.61 μM.
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Flumazenil-d5
0 ImagesCat. No.: HY-W744264CAS No.: 2700278-14-2Flumazenil-d5 is deuterium labeled Flumazenil.
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Vasopressin-d5
0 ImagesCat. No.: HY-B1811S1Synonyms: Arginine vasopressin-d5; Antidiuretic hormone-d5Vasopressin-d5 is anIsotope-labeled compound of Vasopressin. Vasopressin is a cyclic nonapeptide that is synthesized centrally in the hypothalamus. Vasopressin participates in the hypothalamic-pituitary-adrenal axis and regulates pituitary corticotropin secretion by potentiating the stimulatory effects of the corticotropin-releasing factor. Vasopressin also can act as a neurotransmitter, exerting its action by binding to specific G protein-coupled receptors.
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Lixisenatide (Leu-13C6,15N) TFA
0 ImagesCat. No.: HY-P0119SLixisenatide (Leu-13C6,15N) TFA is the 13C- and 15N-labeled Lixisenatide (HY-P0119). Lixisenatide is a glucagon-like peptide-1 (GLP-1) receptor agonist. Lixisenatide inhibits the inflammatory response through down regulation of pro-inflammatory cytokines, and suppresses of the Akt-MEK1/2 signaling pathway. Lixisenatide can inhibit oxidative stress, mitochondrial dysfunction and apoptosis. Lixisenatide can be used for the researches of inflammation, metabolic disease, neurological disease and cardiovascular disease, such as rheumatoid arthritis, diabetes, Alzheimer's disease and atherosclerosis.
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(S)-10-Hydroxycamptothecin-d5
0 ImagesCat. No.: HY-N0095SCAS No.: 1330277-66-1Synonyms: 10-HCPT-d5; 10-Hydroxycamptothecin-d5(S)-10-Hydroxycamptothecin-d5 (10-HCPT-d5) is the deuterium labeled (S)-10-Hydroxycamptothecin. (S)-10-Hydroxycamptothecin (10-HCPT) is a DNA topoisomerase I inhibitor. (S)-10-Hydroxycamptothecin exhibits a remarkable apoptosis-inducing effect. (S)-10-Hydroxycamptothecin has the potential for hepatoma, gastric carcinoma, colon cancer and leukaemia research.
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2-((2,6-Dimethylphenyl)(2-(methoxy-d3)ethyl)amino)-2-oxoacetic acid
0 ImagesCat. No.: HY-W714702S2-((2,6-Dimethylphenyl)(2-(methoxy-d3)ethyl)amino)-2-oxoacetic acid is deuterium labeled 2-((2,6-Dimethylphenyl)(2-methoxyethyl)amino)-2-oxoacetic acid.
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Tiagabine-d4
0 ImagesCat. No.: HY-B0696S1Synonyms: NO050328-d4; NO328-d4; TGB-d4Tiagabine-d4 (NO050328-d4) is deuterium labeled Tiagabine. Tiagabine (NO050328; NO328; TGB) is an orally active, highly selective, and reversible GAT-1 inhibitor and anticonvulsant that crosses the blood-brain barrier. By blocking the reuptake of GABA in neurons and glial cells, tiagabine increases extracellular GABA levels to enhance inhibitory signal transduction, thereby exerting multiple activities such as anticonvulsant, neuroprotective, and antioxidant effects. Tiagabine exhibits linear pharmacokinetic properties. Although it is metabolized by CYP3A and has a high protein binding rate, it carries a low risk of cognitive impairment. Tiagabine is widely used in research on related diseases including epilepsy (including refractory partial seizures), alcohol withdrawal symptoms, and Huntington's disease.
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Mebeverine acid-d3
0 ImagesCat. No.: HY-12769S2Synonyms: Mebeverine metabolite Mebeverine acid-d3Mebeverine acid-d3 (Mebeverine metabolite Mebeverine acid-d3) is the deuterium labeled Mebeverine Acid (HY-12769). Mebeverine acid is a secondary metabolite of the intestinal antispasmodic agent Mebeverine (HY-A0078). Mebeverine acid is generated by the hydrolysis of Mebeverine in the body and is considered a key circulating metabolite. Mebeverine acid is an important marker for oral Mebeverine.
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(Rac)-Rivastigmine-d6
0 ImagesCat. No.: HY-17368S1CAS No.: 194930-04-6Synonyms: (Rac)-ENA 713-d6 free base; (Rac)-SDZ-ENA 713-d6 free base(Rac)-Rivastigmine-d6 is a labelled racemic Rivastigmine. Rivastigmine (ENA 713 free base) is an orally active and potent cholinesterase (ChE) inhibitor and inhibits butyrylcholinesterase (BChE) and acetylcholinesteras (AChE) with IC50s of 0.037 μM , 4.15 μM, respectively. Rivastigmine can pass the blood brain barrier (BBB). Rivastigmine is a parasympathomimetic or cholinergic agent used for the research of mild to moderate dementia of the Alzheimer's type and dementia due to Parkinson's disease.
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(rac)-Dobutamine-d6 hydrochloride
0 ImagesCat. No.: HY-15746S1CAS No.: 1246818-96-1(rac)-Dobutamine-d6 (hydrochloride) is a labelled racemic Dobutamine hydrochloride. Dobutamine hydrochloride is a synthetic catecholamine that acts on α1-AR, β1-AR, β2-AR (α-1, β-1 andβ-2 adrenoceptors). Dobutamine hydrochloride is a selective β1-AR agonist, relatively weak activity at α1-AR and β2-AR. Dobutamine hydrochloride can increase cardiac output and correct hypoperfusion.
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Daurisoline-d11
0 ImagesCat. No.: HY-N0221S2Synonyms: (R,R)-Daurisoline-d11Daurisoline-d11 is the deuterium labeled Daurisoline (HY-N0221). Daurisoline is a bis-benzylisoquinoline alkaloid that can be isolated from Menispermum dauricum and Rhizoma Menispermi. Daurisoline exerts a blocking effect on hERG and has antiarrhythmic effects. Daurisoline is a potent autophagy blocker that can be used for the research of cancer.
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RPR132595A-d3
0 ImagesCat. No.: HY-132545SCAS No.: 1217625-98-3Synonyms: NPC-d3RPR132595A-d3 is the deuterium labeled RPR132595A. RPR132595A is an active metabolite of Irinotecan (CPT-11), which is generated by cytochrome P-450 3A4 (CYP3A4) and finally excreted through urine.
