Lansoprazole sulfone
Based on 1 publication(s) in Google Scholar
Lansoprazole sulfone (AG-1813) is an orally active and selective inhibitor of H+, K+-ATPase. Lansoprazole sulfone can significantly stimulates gastric acid secretion by inhibiting H+, K+-ATPase. Lansoprazole sulfone has potential applications in duodenal ulcer, gastric ulcer, gastroesophageal reflux disease and Zolinger Ellison disease.
For research use only. We do not sell to patients.
- Purity: 99.52%
- CAS No.: 131926-99-3
- Formula: C16H14F3N3O3S
- Molecular Weight:385.36
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Storage:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications Citing Use of MedChemExpress (MCE) Lansoprazole sulfone
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Biological Activity
Chemical Information
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CAS No. 131926-99-3
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Appearance Solid
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Molecular Weight 385.36
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Formula C16H14F3N3O3S
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Color White to off-white
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SMILES
O=S(C1=NC2=CC=CC=C2N1)(CC3=NC=CC(OCC(F)(F)F)=C3C)=O
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Synonyms
AG-1813
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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Acta Pharm Sin B
2024 Apr;14(4):1711-1725. PMID: 38572109
Solvent & Solubility
DMSO : 250 mg/mL (648.74 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (605 KB)
- English - EN (605 KB)
- Français - FR (605 KB)
- Deutsch - DE (605 KB)
- Norwegian - NO (605 KB)
- Español - ES (605 KB)
- Swedish - SV (605 KB)
- Italian - IT (605 KB)
- Korean - KR (605 KB)
- Portuguese - PT (605 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5950 mL | 12.9749 mL | 25.9498 mL | 64.8744 mL |
| 5 mM | 0.5190 mL | 2.5950 mL | 5.1900 mL | 12.9749 mL | |
| 10 mM | 0.2595 mL | 1.2975 mL | 2.5950 mL | 6.4874 mL | |
| 15 mM | 0.1730 mL | 0.8650 mL | 1.7300 mL | 4.3250 mL | |
| 20 mM | 0.1297 mL | 0.6487 mL | 1.2975 mL | 3.2437 mL | |
| 25 mM | 0.1038 mL | 0.5190 mL | 1.0380 mL | 2.5950 mL | |
| 30 mM | 0.0865 mL | 0.4325 mL | 0.8650 mL | 2.1625 mL | |
| 40 mM | 0.0649 mL | 0.3244 mL | 0.6487 mL | 1.6219 mL | |
| 50 mM | 0.0519 mL | 0.2595 mL | 0.5190 mL | 1.2975 mL | |
| 60 mM | 0.0432 mL | 0.2162 mL | 0.4325 mL | 1.0812 mL | |
| 80 mM | 0.0324 mL | 0.1622 mL | 0.3244 mL | 0.8109 mL | |
| 100 mM | 0.0259 mL | 0.1297 mL | 0.2595 mL | 0.6487 mL |