2. Signaling Pathways
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  4. Fluorescent Dye

Fluorescent Dye

Fluorescence is a phenomenon of photoluminescence in luminescence. When an atom is irradiated by light, some electrons around the nucleus jump from their original orbitals to higher energy orbitals under the influence of light energy, i.e., from the ground state to the first or second excited single-line state, etc. Due to the instability of the first or second excited singlet state, the electron returns from the excited singlet state to the ground state accompanied by released energy, resulting in fluorescence.

Fluorescent dyes can be covalently bound or physically adsorbed in the structure of the substance. The fluorescence properties allow for the characterization, localization and quantitative analysis of the labeled object. Fluorescent dyes have shown great potential for the detection of proteins, nucleic acids, cells, and immunoassays, attributed to the advantages in non-radioactive contamination, simple experimental operation and easy observation.

Fluorescent dyes have penetrated many fields such as pharmacology, physiology, environmental science, and information science, as well as functional studies of proteins and drug screening.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-177672C
    FAM labled Zotresiran sodium
    FAM labled Zotresiran sodiumis a FAM labled Zotresiran sodium.
    FAM labled Zotresiran sodium
  • HY-125452
    DiSBAC10
    DiSBAC10 is a voltage-sensitive fluorescent probe used to study cell membrane electrical activity in FRET assays. In a resting polarized cell, DiSBAC10 resides on the outer leaflet of the membrane where it accepts photons from excited fluorescein-labeled proteins and re-emits the photons at a higher wavelength. Depolarization of the cell causes rapid translocation of DiSBAC10 to the inner leaflet of the membrane, thereby increasing the distance between fluorophores and reducing the FRET signal.
    DiSBAC10
  • HY-D1918
    ATTO 390 maleimide
    ATTO 390 maleimide is a maleimide ester derivative of ATTO 390, which can be used to label proteins or antibodies. The maximum excitation/emission wavelength: 390/476 nm.
    ATTO 390 maleimide
  • HY-D1222
    Vat violet 13
    Vat violet 13 is a violet dye.
    Vat violet 13
  • HY-140948
    (5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin
    (5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin is a dye derivative of TAMRA (HY-135640) containing 3 PEG units. (5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    (5,6)TAMRA-PEG3-Azide-PEG3-Desthiobiotin
  • HY-D2550
    Cy5-PEG2000-FA
    Cy5-PEG2000-FA is a fluorescently labeled biomolecule consisting of Cy5 (HY-D0821) fluorescent dye, polyethylene glycol (PEG), and Folic acid (FA) (HY-16637). Cy5 is commonly used in applications such as immunolabeling and nucleic acid labeling. The maximum emission wavelength of Cy5 is approximately 670 nm.
    Cy5-PEG2000-FA
  • HY-D3265
    IR 650 alkyne
    IR 650 Alkyne is a near-infrared fluorescent probe. The click chemistry reaction handle of IR 650 Alkyne is a terminal alkyne, which can undergo a 'copper-catalyzed alkyne-azide cycloaddition' reaction. Ex = 651nm, Em = 668nm.
    IR 650 alkyne
  • HY-D2539
    Cy3-PEG5000-N3
    Cy3-PEG5000-N3 is a Cy3 (HY-D0822)-azide fluorescent dye used to label for protein and nucleic acid. Cy3-PEG5000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Cy3-PEG5000-N3
  • HY-W275616
    4-Methylumbelliferyl nonanoate
    4-Methylumbelliferyl nonanoate is a fluorogenic substrate of esterases. 4-Methylumbelliferyl nonanoate can be hydrolyzed to 4-methylumbelliferone with bright blue fluorescence.
    4-Methylumbelliferyl nonanoate
  • HY-153490D
    FAM labled ISIS 5132 sodium
    FAM labled ISIS 5132 sodiumis a FAM labled ISIS 5132 sodium.
    FAM labled ISIS 5132 sodium
  • HY-132587D
    FAM labled Fitusiran sodium
    FAM labled Fitusiran sodiumis a FAM labled Fitusiran sodium (HY-132587A). Fitusiran (ALN-AT3SC) sodium is a siRNA strategy. Fitusiran delivers siRNA targeting the SERPINC1 gene in hepatocytes to inhibit antithrombin synthesis. Fitusiran sodium enhances thrombin activity and increases Thrombin generation, thereby restoring hemostatic function. Fitusiran sodium can be used in hemophilia-related research.
    FAM labled Fitusiran sodium
  • HY-D2881C
    RB-PEG2000-COOH
    RB-PEG2000-COOH (Rhodamine B-PEG2000-COOH) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and a COOH. RRB-PEG2000-COOH can be used for fluorescent labeling and imaging (Ex/Em=546/610 nm).
    RB-PEG2000-COOH
  • HY-D2190
    Ag2S Oil phase (1200 nm)
    Ag2S Oil phase (1200 nm) is a fluorescent dyes.
    Ag2S Oil phase (1200 nm)
  • HY-177653C
    FAM labled Opemalirsen sodium
    FAM labled Opemalirsen sodiumis a FAM labled Opemalirsen sodium.
    FAM labled Opemalirsen sodium
  • HY-D1124
    Mordant brown 1
    Mordant brown 1, a naphthalenesulphonic acid derivative, is an azo dye. Mordant brown 1 is also an effective and specific inhibitor of CD40-CD154 costimulatory protein-protein interaction.
    Mordant brown 1
  • HY-161502
    DHX-SP
    DHX-SP is a fluorescent probe, which visualizes superoxide anion (O2·–) and peroxynitrite (ONOO–) during ferroptosis of PC12 cells and in the Parkinson’s disease model.
    DHX-SP
  • HY-D2560
    Cy5.5-PEG2000-N3
    Cy5.5-PEG2000-N3 is a Cy5.5 (HY-D0924)-azide fluorescent dye used to label for protein and nucleic acid. Cy5.5-PEG2000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
    Cy5.5-PEG2000-N3
  • HY-D2886H
    RB-PEG10000-N3
    RB-PEG10000-N3 (Rhodamine B-PEG10000-N3) is a fluorescent dye composed of Rhodamine B (HY-Y0016), PEG and azide group (N3). RB-PEG10000-N3 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups (Ex/Em=546/610 nm).
    RB-PEG10000-N3
  • HY-D2794C
    FITC-PEG10000-NH2
    FITC-PEG10000-NH2 is a fluorescent dye composed of polyethylene glycol (PEG), FITC (HY-66019) and an amino group. FITC-PEG10000-NH2 can be used for fluorescent labeling and imaging.
    FITC-PEG10000-NH2
  • HY-D0344
    Giuba Black D
    Direct Grey D exhibits frameshift mutagenic activity.
    Giuba Black D
Cat. No. Product Name / Synonyms Application Reactivity