2442502-32-9
Chemical Structure
HJTA
- CAS No.: 2442502-32-9
- Formula:C28H27N3O6
- Molecular Weight:501.53
InChIKey: PABFIGHOJZEGKD-UHFFFAOYSA-N
SMILES: O=C1C(COC(NC2=CC3=C(NC4=CC=CC=C43)C(C5=CC(OC)=C(C(OC)=C5)OC)=N2)=O)=CCCC1
Biological Activity: HJTA is a selective, pH/GSH dual-responsive Fluorescent probe and anticancer agent. HJTA selectively undergoes an enzymatic reaction with GSTπ. HJTA induces Apoptosis and Autophagy by regulating the expression of apoptotic and autophagic proteins. HJTA exhibits pH- and GSH-dual-responsive fluorescence in tumor cells. HJTA selectively illuminates tumor tissues, enabling precise in situ visualization of colon tumors. HJTA exerts anticancer effects against colon cancer. HJTA can be used for colon cancer research[1].
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HJTA | HJTA is a selective, pH/GSH dual-responsive Fluorescent probe and anticancer agent. HJTA selectively undergoes an enzymatic reaction with GSTπ. HJTA induces Apoptosis and Autophagy by regulating the expression of apoptotic and autophagic proteins. HJTA exhibits pH- and GSH-dual-responsive fluorescence in tumor cells. HJTA selectively illuminates tumor tissues, enabling precise in situ visualization of colon tumors. HJTA exerts anticancer effects against colon cancer. HJTA can be used for colon cancer research. | |||||||||||||||||||||
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Keywords