Insecticide

Insecticides refer to any toxic substances used to kill insects, which exert toxic effects on pests through different mechanisms, thereby achieving the purpose of controlling pest populations and protecting crops and human health. Insecticides have both chemical and biological origins and can be classified into organochlorine insecticides, organophosphorus insecticides, carbamate insecticides, and mineral insecticides based on their chemical properties. Insecticides interact with different target and non-target sites, including receptors, enzymes, and many other known and unknown molecules. Most insecticides are neurotoxicants that target the nervous system, but they can also affect other organs and body systems. Insecticides are metabolized through different metabolic pathways and often serve as biomarkers of exposure in the form of their parent compounds or metabolites. The toxicity of insecticides can be acute, subacute, or chronic, depending on the duration of exposure and the dose involved. Therefore, selecting sensitive, accurate, and validated biomarkers of exposure, effects, and susceptibility appears to be a challenging task.
Insecticides are widely used in agriculture, horticulture, forestry, gardening, homes, offices, and other fields^[1]^[2].

References:

[1]. Sparks TC. Insecticide discovery: an evaluation and analysis. Pestic Biochem Physiol. 2013 Sep;107(1):8-17. [Content Brief]

[2]. Gupta R C, et al. Insecticides[M]//Biomarkers in toxicology. Academic Press, 2019: 455-475.

Insecticide Related Products (469):

By Effects:	Inhibitors (27) Activator (1)

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-W100043

p-Menthane-3,8-diol
p-Menthane-3,8-diol is an insect repellent. p-Menthane-3,8-diol can be used to repel Aedes aegypti.

HY-136081A

Hexamidine diisethionate		98.75%
Hexamidine diisethionate is an antimicrobial agent targeting Acanthamoeba protozoa. Hexamidine diisethionate is promising for research of ocular infectious diseases such as Acanthamoeba keratitis.

HY-177552

4''-Oxoavermectin B1a		98.0%
4''-Oxoavermectin B1a is a potentiator targeting GABA (γ-aminobutyric acid) and glutamate-gated chloride channels with insecticidal and acaricidal activities. 4''-Oxoavermectin B1a is promising for research of agricultural pests.

HY-133204

Chlorfluazuron		98.89%
Chlorfluazuron (IKI-7899) is a benzoylurea insecticide. Chlorfluazuron inhibts insect chitin and disrupts normal exuviation by inducing malformations, thereby preventing and controlling lepidopteran pests.

HY-B0916

Propoxur		99.43%
Propoxur is a reversible, competitive, orally active AChE inhibitor that can cross the blood-brain barrier. Propoxur inhibits AChE activity to induce neurotoxicity, while promoting MMP-2 expression and enhancing tumor cell migration and invasion by inducing intracellular ROS generation and activating the ERK/Nrf2 signaling pathway. On the one hand, Propoxur inhibits AChE, leading to acetylcholine accumulation and causing neurological dysfunction; on the other hand, it promotes Nrf2 nuclear translocation through ROS-dependent ERK1/2 phosphorylation, and upregulates MMP-2 and other invasion-related proteins. Propoxur is also a carbamate insecticide used to combat turf, forestry, and household pests.

HY-119725

Tetradifon		99.78%
Tetradifon is a broad-spectrum organochlorine insecticide and an inhibitor of the mitochondrial oligomycin sensitivity conferring protein (OSCP), which can be used to control a variety of mites. Tetradifon inhibits energy-related activities such as ADP-stimulated respiration, DNP and Mg²⁺-stimulated ATPase, with an IC₅₀ of 4.5-27 nmoL/mg mitochondrial protein. Tetradifon exerts oligomycin-like activity by inhibiting the oxidative phosphorylation process, inducing oxidative stress and interfering with bone metabolism. Tetradifon is currently mainly used in the research of mitochondrial function regulation, bone remodeling mechanism and nephrotoxicity of environmental pollutants.

HY-B1315R

Carbaryl (Standard)
Carbaryl (Standard) is the analytical standard of Carbaryl (HY-B1315). This product is intended for research and analytical applications. Carbaryl is the inhibitor for acetylcholinesterase that inhibits the degradation of acetylcholine in the synaptic cleft, leads to the accumulation of acetylcholine and causes neurotoxicity. Carbaryl can be used as an insecticide.

HY-B1120

Temephos		99.35%
Temephos (Temefos) is an orally active, blood-brain barrier-permeable organophosphate insecticide and AChE inhibitor. By irreversibly inhibiting AChE to induce cholinergic overactivation, Temephos effectively blocks larval development of Aedes aegypti (yellow fever mosquito) and Aedes albopictus (Asian tiger mosquito), and is commonly used in studies related to Dengue Virus, Zika Virus and other relevant pathogens. Temephos exhibits genotoxicity and neurodevelopmental toxicity, and may also cause liver injury, reproductive system abnormalities and cholinergic poisoning symptoms in mammals. Temephos tends to accumulate in adipose tissues and aquatic organisms, and is excreted via feces after metabolism through oxidation and hydrolysis. Note that CYP-mediated metabolic detoxification may reduce the actual larvicidal efficacy of Temephos against some mosquito species. Temephos can be used in research related to dengue fever, Zika virus disease, chikungunya and dracunculiasis.

HY-118659

Benzalphthalide		98.04%
Benzalphthalide (3-Benzylidenephthalide), a phthalate compound, is an insecticide.

HY-W067479

(E)-Cinnamamide		99.35%
(E)-Cinnamamide, the less active isomer of Cinnamamide. Cinnamamide, a derivative of the plant secondary compound Cinnamic acid. Cinnamamide is effective as a non-lethal chemical repellent suitable for reducing avian pest damage.

HY-W040149

Tetramethrin		98.20%
Tetramethrin is a synthetic pyrethroid insecticide for use on a broad spectrum of insect pests.

HY-B0887D

(-)-cis-Permethrin		98.09%
(-)-cis-Permethrin is a pyrethroid insecticide widely used to control many common pests.

HY-W099582

Myristamidopropyl dimethylamine		99.91%
Myristamidopropyl dimethylamine (MAPD) is an antimicrobial agent (including against bacteria and fungi) and an insecticide, exhibiting inhibitory activity against Pseudomonas aeruginosa, Staphylococcus aureus, Candida albicans, Fusarium solani, and Acanthamoeba polyphaga. Myristamidopropyl dimethylamine can be used in research on microbial-induced keratitis .

HY-145297

Flupyrimin		98.14%
Flupyrimin is the antagonist for insect nicotinic acetylcholine receptor (nAChR) that exhibits insecticidal effect by targeting insect nervous system.

HY-17519R

Novaluron (Standard)
Novaluron (Standard) is the analytical standard of Novaluron. This product is intended for research and analytical applications.

HY-W009165R

(Z)-9-Tricosene (Standard)
(Z)-9-Tricosene (Standard) is the analytical standard of (Z)-9-Tricosene. This product is intended for research and analytical applications. (Z)-9-Tricosene (cis-9-Tricosene) is an insect pheromone present in flies of the order Diptera (such as the housefly) and can be used as an insecticide[1].

HY-B0887B

(-)-trans-Permethrin		99.76%
(-)-trans-Permethrin ((-)-trans-NRDC-143) is a pyrethroid that can provide a satisfactory level of protection from black flies for cattle.

HY-P2936A

Sphingomyelin phosphodiesterase, Bacillus cereus
Sphingomyelin phosphodiesterase, Bacillus cereus is a sphingomyelin hydrolase and Insecticide. Sphingomyelin phosphodiesterase, Bacillus cereus catalyzes the decomposition of sphingomyelin into ceramide and phosphorylcholine. Sphingomyelin phosphodiesterase, Bacillus cereus causes rapid paralysis and death in injected insects, including German cockroaches and black cutworms. Sphingomyelin phosphodiesterase, Bacillus cereus reduces H₂O₂ production. Sphingomyelin phosphodiesterase, Bacillus cereus can be used in studies related to sepsis and endophthalmitis.

HY-W042284

Tetradecyl acetate		98.70%
Tetradecyl (Myristyl) acetate is a native sex pheromone component of Yponomeuta rorellus. Tetradecyl acetate elicits orientation behaviour, upwind flight, and landing at the odour source in male Yponomeuta rorellus. Tetradecyl acetate can be used in research on insecticides.

HY-W013170

MGK-264		≥98.0%
MgK-264 (N-octylbicycloheptenedicarboximide) is a synergist enhancing the potency of pyrethroid ingredients. MgK-264 has no intrinsic pesticidal qualities itself.

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