2310-17-0
Chemical Structure
Phosalone
- CAS No.: 2310-17-0
- Formula:C12H15ClNO4PS2
- Molecular Weight:367.81
IUPAC Name: S-((6-chloro-2-oxobenzo[d]oxazol-3(2H)-yl)methyl) O,O-diethyl phosphorodithioate
InChIKey: IOUNQDKNJZEDEP-UHFFFAOYSA-N
SMILES: S=P(OCC)(SCN1C(OC2=CC(Cl)=CC=C12)=O)OCC
Biological Activity: Phosalone is an orally active, blood-brain barrier penetrant Insecticide and acaricide. Phosalone inhibits the activity of Acetylcholinesterase. Phosalone acts as a substrate for detoxifying esterases. Phosalone induces symptoms of cholinergic hyperactivity, toxic reactions, mortality, oxidative stress, and changes in pro-inflammatory protein levels, and exerts toxic effects on colonic tissues and cells. Phosalone controls pistachio psyllids. Phosalone can be used in studies related to colitis[1][2][3].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Phosalone | 98.04% | Phosalone is an orally active, blood-brain barrier penetrant Insecticide and acaricide. Phosalone inhibits the activity of Acetylcholinesterase. Phosalone acts as a substrate for detoxifying esterases. Phosalone induces symptoms of cholinergic hyperactivity, toxic reactions, mortality, oxidative stress, and changes in pro-inflammatory protein levels, and exerts toxic effects on colonic tissues and cells. Phosalone controls pistachio psyllids. Phosalone can be used in studies related to colitis. | ||||||||||||||||||||
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Phosalone (Standard) | ≥98% | Phosalone (Standard) is the analytical standard of Phosalone. This product is intended for research and analytical applications. | ||||||||||||||||||||
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References
- [1]. Pasquet J, et al. Acute oral and percutaneous toxicity of phosalone in the rat, in comparison with azinphosmethyl and parathion. Toxicol Appl Pharmacol. 1976 Jul;37(1):85-92. ID: 968909. [Content Brief]
- [2]. Ghasemi-Niri SF, et al. Phosalone-induced inflammation and oxidative stress in the colon: Evaluation and treatment. World J Gastroenterol. 2016;22(21):4999-5011. [Content Brief]
- [3]. Alizadeh A, et al. Metabolic resistance mechanisms to phosalone in the common pistachio psyllid, Agonoscena pistaciae (Hem.: Psyllidae)[J]. Pesticide Biochemistry and Physiology, 2011, 101(2): 59-64.
