102851-06-9
Chemical Structure
τ-Fluvalinate
- CAS No.: 102851-06-9
- Formula:C26H22ClF3N2O3
- Molecular Weight:502.91
IUPAC Name: cyano(3-phenoxyphenyl)methyl (2-chloro-4-(trifluoromethyl)phenyl)-D-valinate
InChIKey: INISTDXBRIBGOC-XMMISQBUSA-N
SMILES: ClC(C=C(C=C1)C(F)(F)F)=C1N[C@H](C(C)C)C(OC(C2=CC(OC3=CC=CC=C3)=CC=C2)C#N)=O
Biological Activity: τ-Fluvalinate is an insecticide and in-hive miticide, with its mechanism involving interfering with nervous systems. τ-Fluvalinate binds to the open state of Varroa destructor (VdNaV1) and Apis mellifera (AmNaV1) voltage-dependent sodium channels, with EC50 values of 160 nM and 60 nM respectively. τ-Fluvalinate has higher affinity for AmNaV1, which causes sublethal toxicity to honeybees. τ-Fluvalinate can be applied for research on Varroa destructor infestation in honeybee colonies[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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τ-Fluvalinate | 98.32% | τ-Fluvalinate is an insecticide and in-hive miticide, with its mechanism involving interfering with nervous systems. τ-Fluvalinate binds to the open state of Varroa destructor (VdNaV1) and Apis mellifera (AmNaV1) voltage-dependent sodium channels, with EC50 values of 160 nM and 60 nM respectively. τ-Fluvalinate has higher affinity for AmNaV1, which causes sublethal toxicity to honeybees. τ-Fluvalinate can be applied for research on Varroa destructor infestation in honeybee colonies. | ||||||||||||||||||||
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References
- [1]. Wang J, et al. A Novel Sensitive Luminescence Probe Microspheres for Rapid and Efficient Detection of τ-Fluvalinate in Taihu Lake. Sci Rep. 2017;7:46635. Published 2017 May 9. [Content Brief]
- [2]. Gosselin-Badaroudine P, et al. Biophysical characterization of the Varroa destructor NaV1 sodium channel and its affinity for τ-fluvalinate insecticide. FASEB J. 2017 Jul;31(7):3066-3071. [Content Brief]
