2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Lipase

Lipase

Lipase is a water-soluble enzyme that can catalyze the ester bond hydrolysis of lipids, decompose and metabolize fat molecules. Lipase is produced primarily by the pancreas and helps the body digest fats and oils. Lipase inhibitors are able to reduce the digestion and absorption of fat, thereby reducing collective caloric intake and weight loss. Lipase inhibitors are commonly used to suppress diseases such as obesity, hyperlipidemia, and pancreatitis.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-157733
    1,2-Dioleoyl-3-behenoylglycerol
    		Inhibitor 99.9%
    1,2-Dioleoyl-3-behenoylglycerol (BOO) inhibits pancreatic lipase activity. 1,2-Dioleoyl-3-behenoylglycerol prevents the deposition of visceral fat and hepatic triacylglycerol (TAG).
    1,2-Dioleoyl-3-behenoylglycerol
  • HY-135996
    Dilaurylglycerosulfate
    Dilaurylglycerosulfate is a co-emulsifier in the diagnostic test for the determination of lipase.
    Dilaurylglycerosulfate
  • HY-N7668
    Neotheaflavin
    		Inhibitor 99.61%
    Neotheaflavin, from black tea, inhibits pancreatic lipase.
    Neotheaflavin
  • HY-135996A
    Dilaurylglycerosulfate sodium
    		99.85%
    Dilaurylglycerosulfate sodium is a co-emulsifier in the diagnostic test for the determination of lipase.
    Dilaurylglycerosulfate sodium
  • HY-14471R
    Cetilistat (Standard)
    		Inhibitor
    Cetilistat (Standard) is the analytical standard of Cetilistat. This product is intended for research and analytical applications. Cetilistat (ATL-962), an inhibitor of pancreatic lipase, acts as an effective anti-obesity agent. Cetilistat inhibits rat and human pancreatic lipase activity with IC50s of 54.8 nM, and 5.95 nM, respectively.
    Cetilistat (Standard)
  • HY-153860
    LacCer (d18:1/20:0)
    		99.94%
    LacCer (d18:1/20:0) is a lipid whose level is closely associated with atherosclerosis and cardiovascular diseases.
    LacCer (d18:1/20:0)
  • HY-N15385
    Hericenone D
    		Inhibitor 98.20%
    Hericenone D, an orally active pancreatic lipase inhibitor, can be found in Hericium erinaceus. Hericenone D reduces lipid absorption and stimulates nerve growth factor NGF gene expression. Hericenone D can be used for the research of menopausal obesity.
    Hericenone D
  • HY-155837
    hPL-IN-2
    		Inhibitor 98.17%
    hPL-IN-2 (compound 2u) is a potent, reversible, and non-competitive inhibitor of pancreatic lipase (IC50: 1.63 μM) and can be used in anti-obesity research.
    hPL-IN-2
  • HY-Y1422E
    Lipase,Aspergillusniger (Immobilized)
    Lipase, Aspergillus niger (Immobilized) is an immobilized triacylglycerol acyl hydrolase and biocatalyst. Lipase, Aspergillus niger (Immobilized) broadly catalyzes the hydrolysis of glycerol-long-chain fatty acid esters, exhibits positional selectivity for the 1,3-positions of glycerol, but shows low hydrolysis efficiency for castor oil. Lipase, Aspergillus niger (Immobilized) displays optimal activity at 45°C and pH 7.0, and remains stable at temperatures up to 60°C and over a broad pH range of 2.0-9.0. Lipase, Aspergillus niger (Immobilized) is activated by Ca2+ and Mg2+, but inhibited by Mn2+, Fe2+ and Zn2+.
    Lipase,Aspergillusniger (Immobilized)
  • HY-N12297
    Ciwujianoside C2
    		Activator
    Ciwujianoside C2 is a saponin, that can be isolated from the leaves of Acanthopanax senticosus. Ciwujianoside C2 enhances pancreatic lipase activity in vitro.
    Ciwujianoside C2
  • HY-N12292
    Acanthopanaxoside A
    		Inhibitor
    Acanthopanaxoside A, a triterpenoid saponin, has pancreatic lipase inhibitory action.
    Acanthopanaxoside A
  • HY-118481
    H-Pro-Glu-OH
    H-Pro-Glu-OH is a protein secreted by pathogenic mycobacteria through the Type VII secretion system. H-Pro-Glu-OH targets LipY lipases to the cell Surface via the ESX-5 Pathway.
    H-Pro-Glu-OH
  • HY-P992227
    Anti-Endothelial Lipase Antibody
    Anti-Endothelial Lipase Antibody is a monoclonal antibody targeting endothelial lipase. It can be used in ELISA, FACS, and functional assays. For isotype controls of Anti-Endothelial Lipase Antibody, please refer to Human IgG1 kappa, Isotype Control (HY-P99001).
    Anti-Endothelial Lipase Antibody
  • HY-121517
    URB754
    		Inhibitor
    URB754 is a potent inhibitor of the endocannabinoid-deactivating enzyme monoacylglycerol lipase (MGL) with an IC50 of 200 nM.
    URB754
  • HY-165039
    1,3-Dioleoyl-2-octanoyl glycerol
    1,3-Dioleoyl-2-octanoyl glycerol (1,3-Olein-2-caprylin) is a triacylglycerol. 1,3-Dioleoyl-2-octanoyl glycerol can be used to characterize the functionality of R. oryzae lipase for regiodistribution analysis of fats containing medium- and short-chain fatty acids.
    1,3-Dioleoyl-2-octanoyl glycerol
  • HY-B1393R
    Dehydrocholic acid (Standard)
    		Inhibitor
    Dehydrocholic acid (Dehydrocholate) (Standard) is the analytical standard of Dehydrocholic acid (HY-B1393). This product is intended for research and analytical applications. Dehydrocholic acid (Dehydrocholate) is an orally active hydrocholeretic agent. Dehydrocholic acid modulates Autophagy, reduces serum amylase and lipase levels. Dehydrocholic acid has the effects of promoting choleretic function, protecting the liver, reducing pancreatic damage, and regulating cholesterol metabolism. Dehydrocholic acid can be used in the study of acute biliary pancreatitis and obstructive jaundice.
    Dehydrocholic acid (Standard)
  • HY-173296
    MAGL-IN-222
    		Inhibitor
    MAGL-IN-222 (Compound ZQ-7) is a covalent inhibitor targeting monoacylglycerol lipase (MAGL) with an IC50 of 42.31 μM. MAGL-IN-222 can reduce the breakdown of 2-arachidonoylglycerol (2-AG) and increase the intracellular 2-AG level, thereby inhibiting the proliferation and migration of MDA-MB-231 breast cancer cells. MAGL-IN-222 can be used in the research of breast cancer and other related diseases.
    MAGL-IN-222
  • HY-W719455
    Pungenin
    		Inhibitor
    Pungenin is a compound that can be isolated from Leontopodium leontopodioides. Pungenin exhibits lipase inhibitory activity. Pungenin reuduces triglyceride absorption.
    Pungenin
  • HY-W010505S
    Hexane-1,6-diol-d4
    		Substrate
    Hexane-1,6-diol-d4 is the deuterium labeled Hexane-1,6-diol (HY-W010505). Hexane-1,6-diol is a 6-carbon straight-chain diol with hydroxyl groups at both ends. Hexane-1,6-diol can be used as an additive for drilling fluids. Hexane-1,6-diol can also be used as a substrate in life science-related research.
    Hexane-1,6-diol-d<sub>4</sub>
  • HY-Y1422J
    Lipase,Burkholderiacepacia (Immobilized)
    Lipase,Burkholderiacepacia (Immobilized) comes from Burkholderiacepacia and can be used for catalytic reaction.
    Lipase,Burkholderiacepacia (Immobilized)
Cat. No. Product Name / Synonyms Application Reactivity