877804-65-4
Chemical Structure
MAGL-IN-222
- CAS No.: 877804-65-4
- Formula:C22H25N3O4S
- Molecular Weight:427.52
InChIKey: UJQZZXDDELIDKS-UNOMPAQXSA-N
SMILES: CC(/C(C(N1C2CCS(C2)(=O)=O)=O)=C/C3=CC=C(N(CC)CC)C=C3)=C(C#N)C1=O
Biological Activity: MAGL-IN-222 (Compound ZQ-7) is a covalent inhibitor targeting monoacylglycerol lipase (MAGL) with an IC50 of 42.31 μM. MAGL-IN-222 can reduce the breakdown of 2-arachidonoylglycerol (2-AG) and increase the intracellular 2-AG level, thereby inhibiting the proliferation and migration of MDA-MB-231 breast cancer cells. MAGL-IN-222 can be used in the research of breast cancer and other related diseases[1].
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MAGL-IN-222 | MAGL-IN-222 (Compound ZQ-7) is a covalent inhibitor targeting monoacylglycerol lipase (MAGL) with an IC50 of 42.31 μM. MAGL-IN-222 can reduce the breakdown of 2-arachidonoylglycerol (2-AG) and increase the intracellular 2-AG level, thereby inhibiting the proliferation and migration of MDA-MB-231 breast cancer cells. MAGL-IN-222 can be used in the research of breast cancer and other related diseases. | |||||||||||||||||||||
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Keywords
