2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Lipase

Lipase

Lipase is a water-soluble enzyme that can catalyze the ester bond hydrolysis of lipids, decompose and metabolize fat molecules. Lipase is produced primarily by the pancreas and helps the body digest fats and oils. Lipase inhibitors are able to reduce the digestion and absorption of fat, thereby reducing collective caloric intake and weight loss. Lipase inhibitors are commonly used to suppress diseases such as obesity, hyperlipidemia, and pancreatitis.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N14641
    Panclicin A
    		Inhibitor
    Panclicin A is a potent pancreatic lipase inhibitor.
    Panclicin A
  • HY-W674017
    Choline acetate
    		Modulator
    Choline acetate is a choline-based ionic liquid. Choline acetate can promote lipase activity. Choline acetate can also be used as a plasticizer or ionic liquid component to improve carrier structure and release properties, thereby enhancing the performance of biomaterials.
    Choline acetate
  • HY-N14643
    Panclicin C
    		Inhibitor
    Panclicin C is a potent pancreatic lipase inhibitor.
    Panclicin C
  • HY-N0555R
    Escin IB (Standard)
    		Inhibitor
    Escin IB (Standard) is the analytical standard of Escin IB. This product is intended for research and analytical applications. Escin IB is a saponin isolated from skin and the endosperm of seeds of horse chestnut (Aesculus hippocastanum). Escin IB shows inhibitory effect on pancreatic lipase activity.
    Escin IB (Standard)
  • HY-N14647
    Panclicin E
    		Inhibitor
    Panclicin E is a potent pancreatic lipase inhibitor.
    Panclicin E
  • HY-155836
    hPL-IN-1
    		Inhibitor
    hPL-IN-1 (compound 2t) is a reversible inhibitor of pancreatic lipase (PL) (IC50=1.86 μM) for anti-obesity research.
    hPL-IN-1
  • HY-102056R
    BAY 59-9435 (Standard)
    		Inhibitor
    BAY 59-9435 (Standard) is the analytical standard of BAY 59-9435 (HY-102056). This product is intended for research and analytical applications. BAY 59-9435 is a potent and selective inhibitor of Hormone Sensitive Lipase (HSL), with an IC50 of 0.023 μM.
    BAY 59-9435 (Standard)
  • HY-N14646
    Panclicin D
    		Inhibitor
    Panclicin D is a potent pancreatic lipase inhibitor.
    Panclicin D
  • HY-N7859
    1,3-Dioleoyl-2-myristoyl glycerol
    1,3-Dioleoyl-2-myristoyl glycerol is a triacylglycerol that contains oleic acid at the sn-1 and sn-3 positions and myristic acid at the sn-2 position.
    1,3-Dioleoyl-2-myristoyl glycerol
  • HY-N10346A
    Gluconapin
    		Inhibitor
    Gluconapin (3-Butenyl glucosinolate) is an orally active aliphatic glucosinolate and also a flavor modifier. Gluconapin inhibits the elevation of plasma triglyceride levels in mice. Gluconapin also exhibits certain antibacterial activity.
    Gluconapin
  • HY-N14642
    Panclicin B
    		Inhibitor
    Panclicin B is a potent pancreatic lipase inhibitor.
    Panclicin B
  • HY-176006
    1,2-Bis(heptanoylthio)-sn-glycero-3-PE
    1,2-Bis(heptanoylthio)-sn-glycero-3-PE (Diheptanoyl thio-PE) is a sulfur-containing phosphoethanolamine.
    1,2-Bis(heptanoylthio)-sn-glycero-3-PE
  • HY-101509R
    HSL-IN-1 (Standard)
    		Inhibitor
    HSL-IN-1 (Standard) is the analytical standard of HSL-IN-1 (HY-101509). This product is intended for research and analytical applications. HSL-IN-1 (compound 24b) is a potent and orally active hormone sensitive lipase (HSL) inhibitor (IC50=2 nM) with a significantly reduced reactive metabolite liability.
    HSL-IN-1 (Standard)
  • HY-157313
    Pancreatic lipase-IN-1
    		Inhibitor
    Pancreatic lipase-IN-1 (compound 8) ia a pancreatic lipase inhibitor with the Ki of 1.288 μM.
    Pancreatic lipase-IN-1
Cat. No. Product Name / Synonyms Application Reactivity