1. Metabolic Enzyme/Protease Neuronal Signaling NF-κB Immunology/Inflammation
  2. Lipase Cholinesterase (ChE) Reactive Oxygen Species (ROS)
  3. 4'-O-Methylcatechin

4'-O-Methylcatechin acts as a lipase and acetylcholinesterase inhibitor, with an IC50 of 149.93 μM against lipase and an IC50 of 230.89 μM against electric eel-derived acetylcholinesterase. 4'-O-Methylcatechin possesses free radical scavenging activity and can be used in studies on antioxidation, antilipase activity and dementia.

For research use only. We do not sell to patients.

4'-O-Methylcatechin

4'-O-Methylcatechin Chemical Structure

CAS No. : 69912-75-0

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Description

4'-O-Methylcatechin acts as a lipase and acetylcholinesterase inhibitor, with an IC50 of 149.93 μM against lipase and an IC50 of 230.89 μM against electric eel-derived acetylcholinesterase. 4'-O-Methylcatechin possesses free radical scavenging activity and can be used in studies on antioxidation, antilipase activity and dementia[1].

IC50 & Target[1]

electric eel AChE

230.89 μM (IC50)

lipase

149.93 μM (IC50)

In Vitro

4'-O-Methylcatechin inhibits pancreatic lipase activity with an IC50 of 149.93 μM.

4'-O-Methylcatechin inhibits the activity of acetylcholinesterase (AChE) derived from electric eels, and its IC50 is determined to be 230.89 μM via the modified Ellman method using acetylthiocholine iodide as the substrate.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

304.30

Formula

C16H16O6

CAS No.
SMILES

OC1=C2C(O[C@@H]([C@@H](O)C2)C3=CC(O)=C(OC)C=C3)=CC(O)=C1

Structure Classification
Initial Source
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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Product Name:
4'-O-Methylcatechin
Cat. No.:
HY-W740798
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