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Cat. No.: HY-N7163

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(2S)-5,7,3',5'-Tetrahydroxyflavanone

Name: (2S)-5,7,3',5'-Tetrahydroxyflavanone
Brand: MedChemExpress
SKU: HY-N7163
Availability: PreOrder

(Synonyms: (2S)-3',5,5'7-Tetrahydroxyflavanone)

(2S)-5,7,3',5'-Tetrahydroxyflavanone ((2S)-3',5,5'7-Tetrahydroxyflavanone) is a porcine pancreatic lipase modulator with an IC₅₀ of >200 μM against porcine pancreatic lipase. (2S)-5,7,3',5'-Tetrahydroxyflavanone interacts with an enzyme involved in triglyceride hydrolysis.

For research use only. We do not sell to patients.

CAS No.: 160436-10-2
Formula: C₁₅H₁₂O₆
Molecular Weight:288.25

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

(2S)-5,7,3',5'-Tetrahydroxyflavanone Chemical Structure

CAS No.: 160436-10-2

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Protocols (1)
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Cellular Effect

Cell Line	Type	Value	Description	References
RAW264.7	IC₅₀	>100 μM Compound: 16	Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay	[PMID: 23743282]
RAW264.7	IC₅₀	14 μM Compound: 12	Inhibition of LPS/INF-gamma-stimulated nitric oxide production in mouse RAW264.7 cells measured after 16 hrs Inhibition of LPS/INF-gamma-stimulated nitric oxide production in mouse RAW264.7 cells measured after 16 hrs	[PMID: 27955927]

In Vitro

(2S)-5,7,3',5'-Tetrahydroxyflavanone exhibits negligible porcine pancreatic lipase inhibitory activity with an IC₅₀ > 200 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.

Chemical Information

CAS No. 160436-10-2
Molecular Weight 288.25
Formula C₁₅H₁₂O₆
SMILES

OC1=CC(O)=C(C(C[C@@H](C2=CC(O)=CC(O)=C2)O3)=O)C3=C1
Synonyms

(2S)-3',5,5'7-Tetrahydroxyflavanone
Structure Classification
- Flavonoids
- Flavonones
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Cell Biology

Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lee I C, et al. Polyphenolic constituents from the aerial parts of Thymus quinquecostatus var. japonica collected on Ulleung Island[J]. Journal of the Korean Society for Applied Biological Chemistry, 2011, 54: 811-816.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

(2S)-5,7,3',5'-Tetrahydroxyflavanone

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Biological Activity
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- In Vitro
Chemical Information
Protocols
Purity & Documentation
References

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(2S)-5,7,3',5'-Tetrahydroxyflavanone

Biological Activity

Description

Cellular Effect

In Vitro

Chemical Information

Protocols

Purity & Documentation

References

Calculators

Help & FAQs

(2S)-5,7,3',5'-Tetrahydroxyflavanone Related Classifications

HY-N7163 Related Classifications

Bioz

Keywords

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