1. GPCR/G Protein
  2. Glucocorticoid Receptor
  3. Triamcinolone

Triamcinolone 

Cat. No.: HY-B0328 Purity: 99.15%
Handling Instructions

Triamcinolone is a long-acting synthetic corticosteroid.

For research use only. We do not sell to patients.

Triamcinolone Chemical Structure

Triamcinolone Chemical Structure

CAS No. : 124-94-7

Size Price Stock Quantity
Free Sample (0.5-1 mg)   Apply now  
10 mM * 1 mL in DMSO USD 79 In-stock
Estimated Time of Arrival: December 31
100 mg USD 72 In-stock
Estimated Time of Arrival: December 31
500 mg USD 108 In-stock
Estimated Time of Arrival: December 31
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5 g   Get quote  

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Other Forms of Triamcinolone:

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Description

Triamcinolone is a long-acting synthetic corticosteroid. Target: Glucocorticoid Receptor Dimethyl fumarate is an anti-inflammatory. It is indicated for multiple sclerosis patients with relapsing forms and is also being investigated for the treatment of psoriasis. The mechanism of action of dimethyl fumarate in multiple sclerosis is not well understood. It is thought to involve dimethyl fumarate degradation to its active metabolite monomethyl fumarate (MMF) then MMF up-regulates the Nuclear factor (erythroid-derived 2)-like 2 (Nrf2) pathway that is activated in response to oxidative stress [1]. The mean duration of follow-up was 40 months. The rate of decline in the FEV1 after bronchodilator use was similar in the 559 participants in the triamcinolone group and the 557 participants in the placebo group (44.2+/-2.9 vs. 47.0+/-3.0 ml per year, P= 0.50). Members of the triamcinolone group had fewer respiratory symptoms during the course of the study (21.1 per 100 person-years vs. 28.2 per 100 person-years, P=0.005) and had fewer visits to a physician because of a respiratory illness (1.2 per 100 person-years vs. 2.1 per 100 person-years, P=0.03). Those taking triamcinolone also had lower airway reactivity in response to methacholine challenge at 9 months and 33 months (P=0.02 for both comparisons) [2].

Clinical Trial
Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : ≥ 30 mg/mL (76.06 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5353 mL 12.6765 mL 25.3530 mL
5 mM 0.5071 mL 2.5353 mL 5.0706 mL
10 mM 0.2535 mL 1.2677 mL 2.5353 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

394.43

Formula

C₂₁H₂₇FO₆

CAS No.

124-94-7

SMILES
Shipping

Room temperature in continental US; may vary elsewhere

Purity: 99.15%

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Triamcinolone
Cat. No.:
HY-B0328
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Triamcinolone

Cat. No.: HY-B0328