141 Results for "

contacts

" in MedChemExpress (MCE) Product Catalog:
Products (141)

141 Results for "contacts" in MCE Product Catalog:

92
FITC
FITC
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92 Publications Verification
Art. -Nr.: HY-66019
CAS. Nr.: 3326-32-7
Synonyms: Fluorescein 5-isothiocyanate
FITC (Fluorescein Isothiocyanate), is one of the green fluorescein derivatives widely used in biology. FITC has the characteristics of high absorptivity and excellent fluorescence quantum yield. The isothiocyanate group of FITC can be combined with amino, sulfhydryl, imidazole, tyrosyl, carbonyl and other groups on the protein, so as to achieve protein labeling including antibodies and lectins. In addition to its use as a protein marker, FITC can also be used as a fluorescent protein tracer to rapidly identify pathogens by labeling antibodies, or for microsequencing of proteins and peptides (HPLC). The maximum excitation wavelength of FITC is 494 nm. Once excited, it fluoresces yellow-green at a maximum emission wavelength of 520 nm. In addition, FITC is also a hapten that can induce contact hypersensitivity (CHS) and induce an atopic dermatitis model .
16
Yohimbine Hydrochloride
Yohimbine Hydrochloride
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16 Cited Publications
Art. -Nr.: HY-N0127
CAS. Nr.: 65-19-0
Category:  

Alkaloids other families Plants Disease Research Fields Endocrinology Indole Alkaloids

Target:  

Adrenergic Receptor

Yohimbine hydrochloride is an alpha-2 renal adenomatase receptor inhibitor, blocking pre- and post-contact alpha-2 renal adenomatase receptors, causing the release of renal adenoma and multiple sclerosis.
7
Aloperine
Aloperine
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7 Cited Publications
Art. -Nr.: HY-13516
CAS. Nr.: 56293-29-9
Reinheit:  ≥98.0%
Category:  

Infection Alkaloids Piperidine Alkaloids Leguminosae Sophora alopecuroides L Plants Disease Research Fields Inflammation/Immunology

Target:  

Apoptosis Autophagy Filovirus HIV

Aloperine is an alkaloid in sophora plants such as Sophora alopecuroides L, which has shown anti-cancer, anti-inflammatory and anti-virus properties . Aloperine is widely used to treat patients with allergic contact dermatitis eczema and other skin inflammation in China . Aloperine induces apoptosis and autophagy in HL-60 cells .
6
Dimethoate
Dimethoate
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6 Cited Publications
Art. -Nr.: HY-B1946
CAS. Nr.: 60-51-5
Target:  

Environmental Pollutants Apoptosis Cholinesterase (ChE) Insecticide Reactive Oxygen Species (ROS)

Forschungsgebiete:  

Inflammation/Immunology

Dimethoate is an organophosphate insecticide and acaricide. Dimethoate is an orally active acetylcholinesterase inhibitor. Dimethoate induces reactive oxygen species (ROS). Dimethoate induces DNA damage and cell apoptosis in vivo. Dimethoate affect immune system in mice .
4
Epimedin A
Epimedin A
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4 Cited Publications
Art. -Nr.: HY-N0257
CAS. Nr.: 110623-72-8
Category:  

Flavonols Flavonoids Monophenols Other Diseases Phenols Epimedium brevicornu Maxim. Plants Berberidaceae Disease Research Fields

Target:  

PI3K Akt NF-κB NOD-like Receptor (NLR) Keap1-Nrf2 Heme Oxygenase (HO) SOD Caspase Interleukin Related

Epimedin A, one of the main flavonoid active components in Herba Epimedii, is orally active. Epimedin A can inhibit osteoclastogenesis, differentiation, and bone resorption. Epimedin A also possesses anti-inflammatory activity. Epimedin A can be used in the research of osteoporosis and inflammatory diseases .
3
Miclxin
Miclxin
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3 Cited Publications
Art. -Nr.: HY-138301
CAS. Nr.: 2494198-61-5
Reinheit:  99.48%
Synonyms: DS37262926
Target:  

Wnt β-catenin Apoptosis

Forschungsgebiete:  

Cancer

Miclxin (DS37262926) is a potent inhibitor of mutant β-catenin, involving in Wnt signaling pathway. Miclxin induces β-catenin-dependent apoptosis, leads to severe mitochondrial damage with the loss of mitochondrial membrane. Miclxin kills tumor via targeting to MIC60, a major components of the mitochondrial contact site and cristae organizing system (MICOS) complex .
2
Rosin
Rosin
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2 Cited Publications
Art. -Nr.: HY-N0508
CAS. Nr.: 85026-55-7
Category:  

Rhodiola rosea Linn. Simple Phenylpropanols Crassulaceae Phenylpropanoids Plants Disease Research Fields Inflammation/Immunology

Target:  

Others

Rosin is a natural resin extracted from coniferous trees such as pine trees. Rosin is a frequent contact allergen which induces allergic contact dermatitis. Rosin can be used as emulsifiers, adhesives, and other chemical applications .
2
Ampiroxicam
Ampiroxicam
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2 Cited Publications
Art. -Nr.: HY-17484
CAS. Nr.: 99464-64-9
Synonyms: CP 65703
Target:  

Drug Derivative

Forschungsgebiete:  

Inflammation/Immunology

Ampiroxicam is an orally active prodrug of non-steroidal anti-inflammatory drug (NSAID). Ampiroxicam inhibits paw swelling in adjuvant-induced arthritis and acute inflammation models, and suppresses phenylbenzoquinone-induced stretching responses in mice. Ampiroxicam is rapidly and completely converted to Piroxicam (HY-B0253) via non-specific esterases and first-pass metabolism. Ampiroxicam induces contact hypersensitivity and photosensitivity reactions through photoproducts generated by UVA. Ampiroxicam can be used in research related to photosensitivity, adjuvant-induced arthritis, rheumatism, osteoarthritis and other inflammatory diseases .
1
Sodium Picosulfate
Sodium Picosulfate
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1 Cited Publications
Art. -Nr.: HY-B0544
CAS. Nr.: 10040-45-6
Synonyms: Sodium Picosulphate
Target:  

Biochemical Assay Reagents Drug Intermediate

Forschungsgebiete:  

Metabolic Disease

Sodium Picosulfate (Sodium Picosulphate) is a contact irritant laxative with oral activity. Sodium Picosulfate inhibits the absorption of water and electrolytes, increasing their production. Sodium Picosulfate can be used in colonoscopy applications .
1
BI-6901
BI-6901
0 Images
1 Cited Publications
Art. -Nr.: HY-116835
CAS. Nr.: 2040401-92-9
Reinheit:  99.94%
Target:  

CCR

Forschungsgebiete:  

Inflammation/Immunology

BI 6901 is a potent, selective CCR10 antagonist (pIC50=9.0). BI 6901 shows high selectivity over other GPCRs, including a number of other chemokine receptors. BI 6901 is efficacious in the murine DNFB model of contact hypersensitivity and can be used for inflammation research .
1
Diethyl fumarate
Diethyl fumarate
0 Images
1 Cited Publications
Art. -Nr.: HY-W010056
CAS. Nr.: 623-91-6
Category:  

Natural Products Endogenous metabolite Disease Research Fields Inflammation/Immunology

Target:  

Keap1-Nrf2

Diethyl fumarate is a Nrf2 inducer. Diethyl fumarate induces non-immunological contact urticaria, causing erythema, edema, and dose-dependent skin responses characterized by rapid onset, peak response, and subsequent resolution. The hybrid of Diethyl fumarate and Curcumin (HY-N0005) exerts neuroprotective effects. Diethyl fumarate can be used in the research of Parkinson's disease and non-immunological contact urticaria .
1
Pyrimethanil
Pyrimethanil
0 Images
1 Cited Publications
Art. -Nr.: HY-B2033
CAS. Nr.: 53112-28-0
Target:  

Environmental Pollutants Fungal

Forschungsgebiete:  

Infection

Pyrimethanil is an anilinopyrimidine and broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops . Pyrimethanil inhibits the biosynthesis of methionine and other amino acids in Botrytis cinerea. Pyrimethanil can be used for the research of fungal diseases prevention on fruit, vegetable and ornamental plants with mold infection .
1
Poloxamer 237 (F87)
Poloxamer 237 (F87)
0 Images
1 Cited Publications
Art. -Nr.: HY-D1005B
CAS. Nr.: 9003-11-6
Synonyms: PEG-PPG-PEG, 7700 (Average Mn)
Poloxamer 237 (F87) (PEG-PPG-PEG, 7700 (Average Mn)) is an alcohol substance that acts as an oil-in-water emulsifier and solubilizer. Poloxamer 237 (F87) is used in the research of formulations such as contact lens care solutions and eye drops .
1
Pyrethrin II
Pyrethrin II
0 Images
1 Cited Publications
Art. -Nr.: HY-108170
CAS. Nr.: 121-29-9
Reinheit:  31.27%
Category:  

Lycium barbarum L. Natural Products Other Diseases Plants Solanaceae Disease Research Fields Biological Pesticide Research Agricultural Research

Target:  

Insecticide Parasite

Pyrethrin II is an orally active insecticidal ester of chrysanthemum acid found in Chrysanthemum cinerariifolium and C. coccineum Willd., an active constituent of pyrethrum extract with low mammalian toxicity. Pyrethrin II exhibits antiparasitic activity. Pyrethrin II can be used for the research of allergic contact dermatitis and parasitic infections .
1
Spantide II
Spantide II
0 Images
1 Cited Publications
Art. -Nr.: HY-P1722
CAS. Nr.: 129176-97-2
Target:  

Neurokinin Receptor

Forschungsgebiete:  

Inflammation/Immunology

Spantide II, an undecapeptide substance P (SP) analog, is a potent neurokinin-1 receptor (NK-1R) antagonist. Spantide II binds with NK-1R and blocks proinflammatory activities associated with SP. Spantide II can be used in the research of inflammatory skin disorders, such as psoriasis and contact dermatitis .
1
Pyrimethanil (Standard)
Pyrimethanil (Standard)
0 Images
1 Cited Publications
Art. -Nr.: HY-B2033R
CAS. Nr.: 53112-28-0
Target:  

Reference Standards Fungal

Forschungsgebiete:  

Infection

Pyrimethanil (Standard) is the analytical standard of Pyrimethanil. This product is intended for research and analytical applications. Pyrimethanil is an anilinopyrimidine and broad-spectrum contact fungicide for the control of Botrytis spp. on a wide variety of crops . Pyrimethanil inhibits the biosynthesis of methionine and other amino acids in Botrytis cinerea. Pyrimethanil can be used for the research of fungal diseases prevention on fruit, vegetable and ornamental plants with mold infection .
1
Picosulfate sodium salt hydrate
Picosulfate sodium salt hydrate
0 Images
1 Cited Publications
Art. -Nr.: HY-107793
CAS. Nr.: 1307301-38-7
Reinheit:  ≥98.0%
Target:  

Drug Derivative

Forschungsgebiete:  

Metabolic Disease

Picosulfate sodium salt hydrate is the hydrate of Sodium Picosulfate (HY-B0544). Picosulfate sodium salt hydrate is an orally active contact irritant laxative. Picosulfate sodium salt hydrate inhibits the absorption of water and electrolytes, increasing their production. Picosulfate sodium salt hydrate can be used in colonoscopy applications .
1
Polyquaternium-1
Polyquaternium-1
0 Images
1 Cited Publications
Art. -Nr.: HY-127032
CAS. Nr.: 75345-27-6
Reinheit:  ≥99.0%
Synonyms: Polidronium chloride
Target:  

Biochemical Assay Reagents

Forschungsgebiete:  

Infection

Polyquaternium-1 (Polidronium chloride; PQ-1) is an antimicrobial preservative and an activator of NF-κB. Polyquaternium-1 targets bacterial cell membranes, commonly used in ophthalmic surgery. Polyquaternium-1 adsorbs to the surface of microbial membranes through its polycationic properties, destroying membrane integrity and inducing potassium ion leakage, leading to bacterial death. Polyquaternium-1 exerts antimicrobial effects at a concentration of 0.001% and has low toxicity to mammalian cells. Polyquaternium-1 can be used to prepare products such as glaucoma eye drops (Travoprost preparations containing PQ-1), artificial tears, and contact lens solutions to reduce the ocular surface toxicity of traditional preservatives such as benzalkonium chloride (HY-B2232) .
Poly(2-hydroxyethyl methacrylate) (Mv 20000)
Poly(2-hydroxyethyl methacrylate) (Mv 20000)
0 Images
Art. -Nr.: HY-112531
CAS. Nr.: 25249-16-5
Target:  

Biochemical Assay Reagents

Forschungsgebiete:  

Others

Poly(2-hydroxyethyl methacrylate) (MW 20000) is one of the most important hydrogels in the biomaterials world. Poly(2-hydroxyethyl methacrylate) is the basic component of contact lenses, and is also used in implantation of soft tissues, synthetic transplant for gristle and bone, regeneration of neurotic tissue, transmission of agent and etc .
N,N'-Diacetyl-L-cystine
N,N'-Diacetyl-L-cystine
0 Images
Art. -Nr.: HY-114348
CAS. Nr.: 5545-17-5
Reinheit:  98.92%
Synonyms: DiNAC; (Ac-Cys-OH)2
Target:  

Amino Acid Derivatives

Forschungsgebiete:  

Cardiovascular Disease

N,N'-diacetyl-L-cystine (DiNAC) is the disulphide dimer of N-acetylcysteine with immunomodulating properties. N,N'-diacetyl-L-cystine is a potent, orally active modulator of contact sensitivity/delayed type hypersensitivity reactions in rodents. N,N'-diacetyl-L-cystine also has antiatherosclerotic effects in Watanabe-heritable hyperlipidemic rabbit (WHHL) rabbits .
Assay Types