10040-45-6
Chemical Structure
Sodium Picosulfate
Synonym(s): Sodium Picosulphate
- CAS No.: 10040-45-6
- Formula:C18H13NNa2O8S2
- Molecular Weight:481.41
IUPAC Name: sodium (pyridin-2-ylmethylene)bis(4,1-phenylene) bis(sulfate)
InChIKey: GOZDTZWAMGHLDY-UHFFFAOYSA-L
SMILES: O=S(OC1=CC=C(C=C1)C(C2=CC=CC=N2)C3=CC=C(OS(=O)(O[Na])=O)C=C3)(O[Na])=O
Biological Activity: Sodium Picosulfate (Sodium Picosulphate) is a contact irritant laxative with oral activity. Sodium Picosulfate inhibits the absorption of water and electrolytes, increasing their production. Sodium Picosulfate can be used in colonoscopy applications[1][2][3][4].
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Sodium Picosulfate | 98.0% | Sodium Picosulfate (Sodium Picosulphate) is a contact irritant laxative with oral activity. Sodium Picosulfate inhibits the absorption of water and electrolytes, increasing their production. Sodium Picosulfate can be used in colonoscopy applications. | ||||||||||||||||||||
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Sodium Picosulfate (Standard) | ≥98% | Sodium Picosulfate (Standard) is the analytical standard of Sodium Picosulfate. This product is intended for research and analytical applications. Sodium Picosulfate inhibits the absorption of water and electrolytes and increases their secretion. | ||||||||||||||||||||
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- [1]. Nishikawa J, et al. Toxicity study with sodium picosulfate in cultured liver cells of rabbit, rat and man. Arzneimittelforschung. 1981;31(2):321-5. [Content Brief]
- [2]. Geboes K, et al. Effects of 'contact laxatives' on intestinal and colonic epithelial cell proliferation. Pharmacology. 1993 Oct;47 Suppl 1:187-95. [Content Brief]
- [3]. Fioramonti J, et al. In vivo motility of rat colon chronically pretreated with sennosides. Pharmacology. 1993 Oct;47 Suppl 1:155-61. [Content Brief]
- [4]. Regev A, et al. Comparison of two bowel preparations for colonoscopy: sodium picosulphate with magnesium citrate versus sulphate-free polyethylene glycol lavage solution. Am J Gastroenterol. 1998 Sep;93(9):1478-82. [Content Brief]