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  2. Biotin-β-Amyloid (17-40)

Biotin-β-Amyloid (17-40) 

Cat. No.: HY-P2551
Handling Instructions

Biotin-β-Amyloid (17-40) is a N-terminal-labelled biotinylated amyloid-ß-(1-40) peptide. β-Amyloid (17-40) is a 24-residue fragment of the Aβ protein via post-translational processing of amyloid precursor protein (APP).

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Biotin-β-Amyloid (17-40) Chemical Structure

Biotin-β-Amyloid (17-40) Chemical Structure

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Description

Biotin-β-Amyloid (17-40) is a N-terminal-labelled biotinylated amyloid-ß-(1-40) peptide. β-Amyloid (17-40) is a 24-residue fragment of the Aβ protein via post-translational processing of amyloid precursor protein (APP)[1].

In Vitro

β-Amyloid (17-40) (5-10 μM) increases the rate of Aβ (1-40) aggregation more than addition of equivalent amounts of β-Amyloid (17-28), because it facilitates aggregation of Aβ40 through two different mechanisms, one promoted by residues 17-21 and the second by residues 30-35[1]. Biotin is widely used throughout the biotechnology industry to conjugate proteins for biochemical assays. Biotin can be used for qualitative and quantitative detection, labelling or immobilisation.

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

2619.20

Formula

C₁₂₀H₁₉₂N₂₈O₃₃S₂

Sequence Shortening

Biotin-LVFFAEDVGSNKGAIIGLMVGGVV

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

Biotin-β-Amyloid (17-40)OthersaggregationAβ40BiotinylatedInhibitorinhibitorinhibit

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Biotin-β-Amyloid (17-40)
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HY-P2551
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