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  2. Biotin-β-Amyloid (17-40)

Biotin-β-Amyloid (17-40) 

Cat. No.: HY-P2551
Handling Instructions

Biotin-β-Amyloid (17-40) is a N-terminal-labelled biotinylated amyloid-ß-(1-40) peptide. β-Amyloid (17-40) is a 24-residue fragment of the Aβ protein via post-translational processing of amyloid precursor protein (APP).

For research use only. We do not sell to patients.

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Biotin-β-Amyloid (17-40) Chemical Structure

Biotin-β-Amyloid (17-40) Chemical Structure

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Description

Biotin-β-Amyloid (17-40) is a N-terminal-labelled biotinylated amyloid-ß-(1-40) peptide. β-Amyloid (17-40) is a 24-residue fragment of the Aβ protein via post-translational processing of amyloid precursor protein (APP)[1].

In Vitro

β-Amyloid (17-40) (5-10 μM) increases the rate of Aβ (1-40) aggregation more than addition of equivalent amounts of β-Amyloid (17-28), because it facilitates aggregation of Aβ40 through two different mechanisms, one promoted by residues 17-21 and the second by residues 30-35[1]. Biotin is widely used throughout the biotechnology industry to conjugate proteins for biochemical assays. Biotin can be used for qualitative and quantitative detection, labelling or immobilisation.

Molecular Weight

2619.20

Formula

C₁₂₀H₁₉₂N₂₈O₃₃S₂

Sequence Shortening

Biotin-LVFFAEDVGSNKGAIIGLMVGGVV

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Keywords:

Biotin-β-Amyloid (17-40)OthersaggregationAβ40BiotinylatedInhibitorinhibitorinhibit

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Biotin-β-Amyloid (17-40)
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