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Cat. No.: HY-13202R

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T0070907 (Standard)

T0070907 (Standard) is the analytical standard of T0070907. This product is intended for research and analytical applications. T0070907 is a potent PPARγ antagonist with a Ki of 1 nM.

For research use only. We do not sell to patients.

CAS No.: 313516-66-4
Formula: C₁₂H₈ClN₃O₃
Molecular Weight:277.66

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

T0070907 (Standard) Chemical Structure

CAS No.: 313516-66-4

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Product Information
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Chemical Information
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Product Information

Information

T0070907 (Standard) is the analytical standard of T0070907. This product is intended for research and analytical applications. T0070907 is a potent PPARγ antagonist with a Ki of 1 nM.

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 313516-66-4
Molecular Weight 277.66
Formula C₁₂H₈ClN₃O₃
SMILES

ClC1=C(C=C(C=C1)[N+]([O-])=O)C(NC2=CC=NC=C2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. An Z, et al. T0070907 inhibits repair of radiation-induced DNA damage by targeting RAD51. Toxicol In Vitro. 2016 Dec;37:1-8 [Content Brief]

[2]. An Z, et al. T0070907, a PPAR γ inhibitor, induced G2/M arrest enhances the effect of radiation in human cervical cancer cells through mitotic catastrophe. Reprod Sci. 2014 Nov;21(11):1352-61. [Content Brief]

[3]. Kawahara A, et al. Peroxisome proliferator-activated receptor γ (PPARγ)-independent specific cytotoxicity against immature adipocytes induced by PPARγ antagonist T0070907. Biol Pharm Bull. 2013;36(9):1428-34 [Content Brief]

[4]. Lee G, et al. T0070907, a selective ligand for peroxisome proliferator-activated receptor gamma, functions as an antagonist of biochemical and cellular activities. J Biol Chem. 2002 May 31;277(22):19649-57. Epub 2002 Mar 4 [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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