8-Chloro caffeine
Based on 1 Customer Validation
8-Chloro caffeine binds to adenosine receptors (Ki = 30 µM). 8-Chloro caffeine potentiates UV-induced chromosomal aberrations in Cl-I Chinese hamster embryonic lung cells. 8-Chloro caffeine is a derivative of the methylxanthine alkaloid caffeine.
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- Pureté: 98.52%
- CAS No.: 4921-49-7
- Formule: C8H9ClN4O2
- Masse moléculaire:228.64
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Stockage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Voir tous les produits spécifiques à Isoform Adenosine Receptor
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Activité biologique
Chemical Information
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CAS No. 4921-49-7
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Appearance Solid
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Masse moléculaire 228.64
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Formule C8H9ClN4O2
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Color White to off-white
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SMILES
O=C1C2=C(N(C)C(N1C)=O)N=C(N2C)Cl
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
DMSO : 8.33 mg/mL (36.43 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Nilsson K, et al. The effect of methylated oxypurines on the size of newly-synthesized DNA and on the production of chromosome aberrations after UV irradiation in Chinese hamster cells. Mutat Res. 1975 Nov;30(2):255-66. [Content Brief]
[2]. Bruns RF. Adenosine antagonism by purines, pteridines and benzopteridines in human fibroblasts. Biochem Pharmacol. 1981 Feb 15;30(4):325-33. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.3737 mL | 21.8684 mL | 43.7369 mL | 109.3422 mL |
| 5 mM | 0.8747 mL | 4.3737 mL | 8.7474 mL | 21.8684 mL | |
| 10 mM | 0.4374 mL | 2.1868 mL | 4.3737 mL | 10.9342 mL | |
| 15 mM | 0.2916 mL | 1.4579 mL | 2.9158 mL | 7.2895 mL | |
| 20 mM | 0.2187 mL | 1.0934 mL | 2.1868 mL | 5.4671 mL | |
| 25 mM | 0.1749 mL | 0.8747 mL | 1.7495 mL | 4.3737 mL | |
| 30 mM | 0.1458 mL | 0.7289 mL | 1.4579 mL | 3.6447 mL |
8-Chloro caffeine Related Classifications
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