4921-49-7
4921-49-7
Chemical Structure
8-Chloro caffeine
- CAS No.: 4921-49-7
- Formula:C8H9ClN4O2
- Molecular Weight:228.64
IUPAC Name: 8-chloro-1,3,7-trimethyl-3,7-dihydro-1H-purine-2,6-dione
InChIKey: HGKPGBJNNATDRR-UHFFFAOYSA-N
SMILES: O=C1C2=C(N(C)C(N1C)=O)N=C(N2C)Cl
Biological Activity: 8-Chloro caffeine binds to adenosine receptors (Ki = 30 µM). 8-Chloro caffeine potentiates UV-induced chromosomal aberrations in Cl-I Chinese hamster embryonic lung cells. 8-Chloro caffeine is a derivative of the methylxanthine alkaloid caffeine[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
8-Chloro caffeine | 98.52% | 8-Chloro caffeine binds to adenosine receptors (Ki = 30 µM). 8-Chloro caffeine potentiates UV-induced chromosomal aberrations in Cl-I Chinese hamster embryonic lung cells. 8-Chloro caffeine is a derivative of the methylxanthine alkaloid caffeine. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
References
- [1]. Nilsson K, et al. The effect of methylated oxypurines on the size of newly-synthesized DNA and on the production of chromosome aberrations after UV irradiation in Chinese hamster cells. Mutat Res. 1975 Nov;30(2):255-66. [Content Brief]
- [2]. Bruns RF. Adenosine antagonism by purines, pteridines and benzopteridines in human fibroblasts. Biochem Pharmacol. 1981 Feb 15;30(4):325-33. [Content Brief]
Keywords
