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Cat. No.: HY-111467

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Mcl1-IN-4

Mcl1-IN-4 is an inhibitor of Mcl1 with an IC₅₀ of 0.2 μM.

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CAS No.: 1580484-04-3
Formule: C₂₈H₂₆N₂O₅S
Masse moléculaire:502.58

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Mcl1-IN-4 Chemical Structure

CAS No.: 1580484-04-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Mcl1-IN-4 is an inhibitor of Mcl1 with an IC₅₀ of 0.2 μM.

IC₅₀ & Target

IC50: 0.2 μM (Mcl1)^[1]

Voir tous les produits spécifiques à Isoform Bcl-2 Family :

In Vitro

Mcl1-IN-4 is compound 19^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1580484-04-3
Masse moléculaire 502.58
Formule C₂₈H₂₆N₂O₅S
SMILES

CC1=C2C(C=CC=C2)=C(C3=CC(NS(C4=CC(N5CCOCC5)=CC=C4)(=O)=O)=C(C(O)=O)C=C3)C=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Petros AM, et al. Fragment-based discovery of potent inhibitors of the anti-apoptotic MCL-1 protein. Bioorg Med Chem Lett. 2014 Mar 15;24(6):1484-8. [Content Brief]

[2]. Petros A, et al. Fragment-based Discovery of Potent Inhibitors of the Anti-Apoptotic MCL-1 Protein. Bioorg Med Chem Lett, 24 (6), 1484-1488.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références

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Mcl1-IN-4

Voir tous les produits spécifiques à Isoform Bcl-2 Family

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Mcl1-IN-4 Related Classifications

HY-111467 Related Classifications