Antitrypanosomal agent 19
Antitrypanosomal agent 19 (compound 10) is an orally available antitrypanosomal agent. Antitrypanosomal agent 19 effectively inhibits the growth of trypanosomatids T. b. brucei, T. b. gambiense and T. b. rhodesiense, mitigating the Human trypanosomiasis (HAT)-induced acute infectious toxicity in mice.
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- Formule: C10H11N3O4S
- Masse moléculaire:269.28
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Trypanosome[1]
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | CC50 |
>75 μM
Compound: 10
|
Cytotoxicity against human HepG2 cells assessed as cell growth measured after 72 hrs mby MTT assay
Cytotoxicity against human HepG2 cells assessed as cell growth measured after 72 hrs mby MTT assay
|
[PMID: 37984297] |
Chemical Information
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Masse moléculaire 269.28
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Formule C10H11N3O4S
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SMILES
O=C(C1=CC=C([N+]([O-])=O)S1)NC/C=C/C(NC)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)