GRAMD1B - GRAM domain containing 1B Gene

Also Known as LINC01059

Species: Homo sapiens

Gene Type: protein coding
Gene ID: 57476

About GRAMD1B

This gene has 17 transcripts (splice variants), 272 orthologues and 4 paralogues. Biased expression in adrenal (RPKM 12.4), duodenum (RPKM 5.7) and 11 other tissues.

Summary

Predicted to enable Cholesterol binding activity; Cholesterol transfer activity; and phospholipid binding activity. Predicted to be involved in cellular response to Cholesterol and Cholesterol homeostasis. Located in endoplasmic reticulum membrane; endoplasmic reticulum-plasma membrane contact site; and plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]

GRAMD1B Products (20)

mRNA Protein Name
NM_001286563.3 NP_001273492.1 protein Aster-B isoform 1
NM_001286564.3 NP_001273493.1 protein Aster-B isoform 3
NM_001330396.3 NP_001317325.1 protein Aster-B isoform 4
NM_001354837.2 NP_001341766.1 protein Aster-B isoform 9
NM_001367418.2 NP_001354347.1 protein Aster-B isoform 5
NM_001367419.2 NP_001354348.1 protein Aster-B isoform 6
NM_001367420.2 NP_001354349.1 protein Aster-B isoform 7
NM_001367421.2 NP_001354350.1 protein Aster-B isoform 8
NM_001387024.1 NP_001373953.1 protein Aster-B isoform 10
NM_001387025.1 NP_001373954.1 protein Aster-B isoform 11
NM_001387026.1 NP_001373955.1 protein Aster-B isoform 12
NM_001387028.1 NP_001373957.1 protein Aster-B isoform 13
NM_001387029.1 NP_001373958.1 protein Aster-B isoform 14
NM_001387030.1 NP_001373959.1 protein Aster-B isoform 15
NM_001387031.1 NP_001373960.1 protein Aster-B isoform 15
NM_001387032.1 NP_001373961.1 protein Aster-B isoform 3
NM_001387033.1 NP_001373962.1 protein Aster-B isoform 3
NM_001387034.1 NP_001373963.1 protein Aster-B isoform 4
NM_001387035.1 NP_001373964.1 protein Aster-B isoform 4
NM_020716.4 NP_065767.1 protein Aster-B isoform 2

Gene Ontology

  • Cellular Component
Cellular Component GO Annotation Evidence Références Source
located in endoplasmic reticulum membrane IDA
IDA: Inferred from direct assay
30220461 GOA
located in endoplasmic reticulum-plasma membrane contact site IDA
IDA: Inferred from direct assay
30220461 GOA
located in plasma membrane IDA
IDA: Inferred from direct assay
30220461 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern

GRAMD1B Protein Structure

GRAM

GRAM: GRAM domain (96 - 162)

  • 0
  • 200
  • 400
  • 600
  • 738 a.a.
Protein Preferred Names Protein Names

protein Aster-B

  • GRAM domain-containing protein 1B

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (1)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS05773 GRAMD1B Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Rattus norvegicus GRAMD1B RGD RGD:1305443
Macaca mulatta GRAMD1B VGNC VGNC:73028
Mus musculus GRAMD1B MGD MGI:1925037
Felis catus GRAMD1B VGNC VGNC:62702
Bos taurus GRAMD1B VGNC VGNC:29623
Canis familiaris GRAMD1B VGNC VGNC:41466
Others GRAMD1B NCBI