Balanophonin B
Balanophonin B is a selective inhibitor (IC50=1.46 μg/mL) that targets the lipopolysaccharide (LPS)-induced nitric oxide (NO) production pathway and can be isolated from Lithocarpus pachylepis. Balanophonin B inhibits the production of NO in LPS-stimulated RAW264.7 macrophages and exerts anti-inflammatory activity to reduce the inflammatory response. Balanophonin B can be used for anti-inflammatory drug development and biological activity research of natural lignan compounds.
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- CAS. Nr.: 92216-41-6
- Formel: C20H20O7
- Molecular Weight:372.37
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
40 μg/mL
Compound: 5
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Cytotoxicity against human A549 cells after 48 hrs by SRB assay
Cytotoxicity against human A549 cells after 48 hrs by SRB assay
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[PMID: 18603435] |
Chemical Information
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CAS. Nr. 92216-41-6
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Molecular Weight 372.37
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Formel C20H20O7
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SMILES
O=C1[C@@]2([H])[C@@](CO[C@@H]2C3=CC(OC)=C(C=C3)O)([H])[C@@H](C4=CC(OC)=C(C=C4)O)O1
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Balanophonin B Related Classifications
HY-N16774 Related Classifications
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