- Natural Products
- Plants
- Fagaceae
- Lithocarpus pachylepis A. Camus
Lithocarpus pachylepis A. Camus
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Lithocarpus pachylepis A. Camus (1)
- Formula: C20H20O7
- Molecular Weight: 372.37
Balanophonin B is a selective inhibitor (IC50=1.46 μg/mL) that targets the lipopolysaccharide (LPS)-induced nitric oxide (NO) production pathway and can be isolated from Lithocarpus pachylepis. Balanophonin B inhibits the production of NO in LPS-stimulated RAW264.7 macrophages and exerts anti-inflammatory activity to reduce the inflammatory response. Balanophonin B can be used for anti-inflammatory drug development and biological activity research of natural lignan compounds.
August 31
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August 31
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