DXR-IN-1
DXR-IN-1 (Compound 13E) is an inhibitor of 1-deoxy-D-ketose 5-phosphate reductoisomerase (DXR). DXR-IN-1 is highly selective for P. falciparum DXR (IC50=0.030 μM). DXR-IN-1 inhibits the growth of P. falciparum by binding to the active site of DXR and blocking its catalytic activity.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C19H24NO5P
- Molecular Weight:377.37
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
DXR-IN-1 inhibits DXR with IC50=0.035 μM (E. coll), 3.0 μM (M. tuberculosis), respectively[1].
DXR-IN-1 anti-Plasmodium activity is IC50=0.55 μM (Pf3D7), 0.94 μM (PfDd2), respectively[1].
DXR-IN-1 cytotoxicity is IC50=>1000 μM (HepG-2)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 377.37
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Formel C19H24NO5P
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SMILES
ON(C(CCC(C1=CC=CC=C1)P(O)(O)=O)=O)CCCC2=CC=CC=C2
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
DXR-IN-1 Related Classifications
HY-158335 Related Classifications
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