Phosphodiesterase-IN-2
Phosphodiesterase-IN-2 (Compound C7) is a selective, orally active inhibitor for phosphodiesterase 10A (PDE10A), with an IC50 of 11.9 nM. Phosphodiesterase-IN-2 improves the stability of liver microsomes, and lowers BBB permeability. Phosphodiesterase-IN-2 exhibits good pharmacokinetic characters, and attenuates isoprenaline (HY-108353)-induced cardiac hypertrophic in mouse models.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 3047610-96-5
- Formel: C32H27F3N6O2
- Molecular Weight:584.59
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Biologische Aktivität
|
PDE10A 11.9 nM (IC50) |
Chemical Information
-
CAS. Nr. 3047610-96-5
-
Molecular Weight 584.59
-
Formel C32H27F3N6O2
-
SMILES
FC(F)(F)C(C=C1C2=CC(C)=NC=C2)=NN1C3=CC=C(OCC4=NC5=C(C=CC=C5)C(C(N6CC7(CNC7)C6)=O)=C4)C=C3
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Phosphodiesterase-IN-2 Related Classifications
HY-161663 Related Classifications
Powered by Bioz