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Art. -Nr.: HY-121755

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Tibric acid

(Synonyms: CP 18524)

Tibric acid (CP 18524) has similar effects to those of hypolipidemic agents. Tibric acid has orally active triglyceride-lowering effects. Tibric acid can be used for research of hypertriglyceridemia.

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CAS. Nr.: 37087-94-8
Formel: C₁₄H₁₈ClNO₄S
Molecular Weight:331.82

Speicherung:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

Data Sheet (269 KB)

Tibric acid Chemical Structure

CAS. Nr.: 37087-94-8

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Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vivo
Chemical Information
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Biologische Aktivität

Beschreibung

Tibric acid (CP 18524) has similar effects to those of hypolipidemic agents. Tibric acid has orally active triglyceride-lowering effects. Tibric acid can be used for research of hypertriglyceridemia^[1]^[2].

IC₅₀ & Target

PPARα

Alle PPAR Isoform-spezifische Produkte anzeigen :

In Vivo

Tibric acid (13-125 mg/kg/d, oral administration, daily for 1 week) reduces serum cholesterol and triglyceride levels in rats^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model:

Rats^[1]
Dosage:

13, 25, 125 mg/kg/d
Administration:

oral administration, daily for 1 week
Result:

Decreased serum cholesterol and triglyceride levels, but increased total liver content of cholesterol, phospholipids, and triglycerides.

Chemical Information

CAS. Nr. 37087-94-8
Appearance Solid
Molecular Weight 331.82
Formel C₁₄H₁₈ClNO₄S
Color White to off-white
SMILES

O=C(C1=CC(S(=O)(N2C[C@H](C[C@H](C2)C)C)=O)=CC=C1Cl)O
Synonyms

CP 18524
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Bielmann P, et al. Dose-response to tibric acid: a new hypolipidemic drug in type IV hyperlipoproteinemia. Clin Pharmacol Ther. 1975 May;17(5):606-11. [Content Brief]

[2]. Cayen MN, et al. Effect of tibric acid on hepatic cholesterol synthesis in rats. Lipids. 1977 Aug;12(8):684-8. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Tibric acid

Alle PPAR Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Tibric acid Related Classifications

HY-121755 Related Classifications