Toltrazuril sulfoxide
Based on 1 publication(s) in Google Scholar
Toltrazuril sulfoxide is a short-lived intermediary metabolite of Toltrazuril (HY-B0175), and then can be metabolized to the reactive toltrazuril sulfone (TZR-SO2) in vivo. Toltrazuril is an antiprotozoal agent that acts upon Coccidia parasites.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 99.55%
- CAS. Nr.: 69004-15-5
- Formel: C18H14F3N3O5S
- Molecular Weight:441.38
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Speicherung:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Publications Citing Use of MedChemExpress (MCE) Toltrazuril sulfoxide
MoreAlle Endogenous Metabolite Isoform-spezifische Produkte anzeigen
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Biologische Aktivität
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Coccidia |
Chemical Information
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CAS. Nr. 69004-15-5
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Appearance Solid
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Molecular Weight 441.38
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Formel C18H14F3N3O5S
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Color White to off-white
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SMILES
O=C(N(C1=CC=C(OC2=CC=C(S(C(F)(F)F)=O)C=C2)C(C)=C1)C(N3)=O)N(C)C3=O
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Pestic Biochem Physiol
2025 Sep:213:106524. PMID: 40744572
Lösungsmittel & Löslichkeit
DMSO : 250 mg/mL (566.41 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (272 KB)
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SDS (537 KB)
- English - EN (537 KB)
- Français - FR (537 KB)
- Deutsch - DE (537 KB)
- Norwegian - NO (537 KB)
- Español - ES (537 KB)
- Swedish - SV (537 KB)
- Italian - IT (537 KB)
- Korean - KR (537 KB)
- Portuguese - PT (537 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Jong-Hwan Lim, et al. Pharmacokinetics of toltrazuril and its metabolites, toltrazuril sulfoxide and toltrazuril sulfone, after a single oral administration to pigs. J Vet Med Sci. 2010 Aug;72(8):1085-7. [Content Brief]
[2]. H Mehlhorn, et al. Toltrazuril effective against a broad spectrum of protozoan parasites. Parasitol Res. 1988;75(1):64-6. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2656 mL | 11.3281 mL | 22.6562 mL | 56.6405 mL |
| 5 mM | 0.4531 mL | 2.2656 mL | 4.5312 mL | 11.3281 mL | |
| 10 mM | 0.2266 mL | 1.1328 mL | 2.2656 mL | 5.6641 mL | |
| 15 mM | 0.1510 mL | 0.7552 mL | 1.5104 mL | 3.7760 mL | |
| 20 mM | 0.1133 mL | 0.5664 mL | 1.1328 mL | 2.8320 mL | |
| 25 mM | 0.0906 mL | 0.4531 mL | 0.9062 mL | 2.2656 mL | |
| 30 mM | 0.0755 mL | 0.3776 mL | 0.7552 mL | 1.8880 mL | |
| 40 mM | 0.0566 mL | 0.2832 mL | 0.5664 mL | 1.4160 mL | |
| 50 mM | 0.0453 mL | 0.2266 mL | 0.4531 mL | 1.1328 mL | |
| 60 mM | 0.0378 mL | 0.1888 mL | 0.3776 mL | 0.9440 mL | |
| 80 mM | 0.0283 mL | 0.1416 mL | 0.2832 mL | 0.7080 mL | |
| 100 mM | 0.0227 mL | 0.1133 mL | 0.2266 mL | 0.5664 mL |
Toltrazuril sulfoxide Related Classifications
HY-136438 Related Classifications
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