WNT7A-IN-1
Based on 1 Customer Validation
WNT7A-IN-1 (1365-0109), a WNT7A inhibitor, disrupts the protein-protein interaction between WNT7A and its receptor FZD5, resulting in the upregulation of MHC-I expression. WNT7A-IN-1 significantly increases the expression of MHC-I and p-p65,while concurrently reducing the expression of active β-catenin. WNT7A-IN-1 (compound F) is also a photographic sensitizer in the green spectral region.
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- Reinheit: 99.66%
- CAS. Nr.: 29133-39-9
- Formel: C37H36N2O8S2
- Molecular Weight:700.82
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Speicherung:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biologische Aktivität
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Wnt7A |
Chemical Information
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CAS. Nr. 29133-39-9
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Appearance Solid
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Molecular Weight 700.82
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Formel C37H36N2O8S2
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Color Orange to red
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SMILES
O=S([O-])(CCC[N+]1=C(/C=C(CC)/C=C2OC3=C(N\2CCCS(=O)(O)=O)C=C(C4=CC=CC=C4)C=C3)OC5=CC=C(C6=CC=CC=C6)C=C51)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Lösungsmittel & Löslichkeit
DMSO : 70 mg/mL (99.88 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (274 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.4269 mL | 7.1345 mL | 14.2690 mL | 35.6725 mL |
| 5 mM | 0.2854 mL | 1.4269 mL | 2.8538 mL | 7.1345 mL | |
| 10 mM | 0.1427 mL | 0.7134 mL | 1.4269 mL | 3.5672 mL | |
| 15 mM | 0.0951 mL | 0.4756 mL | 0.9513 mL | 2.3782 mL | |
| 20 mM | 0.0713 mL | 0.3567 mL | 0.7134 mL | 1.7836 mL | |
| 25 mM | 0.0571 mL | 0.2854 mL | 0.5708 mL | 1.4269 mL | |
| 30 mM | 0.0476 mL | 0.2378 mL | 0.4756 mL | 1.1891 mL | |
| 40 mM | 0.0357 mL | 0.1784 mL | 0.3567 mL | 0.8918 mL | |
| 50 mM | 0.0285 mL | 0.1427 mL | 0.2854 mL | 0.7134 mL | |
| 60 mM | 0.0238 mL | 0.1189 mL | 0.2378 mL | 0.5945 mL | |
| 80 mM | 0.0178 mL | 0.0892 mL | 0.1784 mL | 0.4459 mL |